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NCT00323323 · ClinicalTrials.gov registry record · Phase 1

CHOP and Campath-1H in Previously Untreated Aggressive T/NK-Cell Lymphomas

A Phase 1 study, sponsored by Ohio State University Comprehensive Cancer Center.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT00323323: Completed Phase 1 study, sponsored by Ohio State University Comprehensive Cancer Center.

NCT00323323 is a Phase 1 study that has completed, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00323323, a Phase 1 study, has completed, sponsored by Ohio State University Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

Purpose: This study will evaluate the safety of CHOP plus Alemtuzumab in patients with T/NK cell lymphomas and CD-20 negative large B-cell lymphomas who have not had previous treatments. The biological response of lymphoma cells and the immune system to this drug combination will also be measured in patients before, during, and after therapy administration.

Interventions

  • DRUG Alemtuzumab
  • DRUG CHOP
  • PROCEDURE Plasma Samples

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2004-03
Est. Completion 2016-10
Phase Phase 1

What the finished NCT00323323 record still lists

NCT00323323 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 3 interventions - of which Alemtuzumab is the first listed.

NCT00323323 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00323323 about?

NCT00323323 is a clinical study titled "CHOP and Campath-1H in Previously Untreated Aggressive T/NK-Cell Lymphomas". Purpose: This study will evaluate the safety of CHOP plus Alemtuzumab in patients with T/NK cell lymphomas and CD-20 negative large B-cell lymphomas who have not had previous treatments. The biological response of lymphoma cells and the immune system to this drug combination will also be measured in...

What is the current status of trial NCT00323323?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2004-03. Estimated completion is 2016-10.

What interventions are being tested in trial NCT00323323?

The interventions under investigation include: Alemtuzumab (DRUG), CHOP (DRUG), Plasma Samples (PROCEDURE).

Who is sponsoring clinical trial NCT00323323?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00323323's enrollment target sits among peer trials

24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00323323, the US trial registry maintained by the National Library of Medicine. NCT00323323 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.