Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00320710 · ClinicalTrials.gov registry record · Phase 3

Continued Efficacy and Safety of Zoledronic Acid (q 4 Wks vs. q 12 Wks) in the 2nd Year of Treatment in Patients With Bone Metastases From Breast Cancer

A Phase 3 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
416
Enrollment target

NCT00320710: Completed Phase 3 study, sponsored by Novartis Pharmaceuticals.

NCT00320710 is a Phase 3 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 416 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (46% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00320710, a Phase 3 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
416 participants
Enrollment target

Study Summary

Clinical trial in breast cancer patients with bone metastases pretreated for approximately 1 year with a standard zoledronic acid regimen. Looking at the continued effectiveness and safety of giving zoledronic acid every 4 weeks versus every 12 weeks given over 1 year. This study is prospective, double-blind, stratified, multi-center, and two-arm.

Primary Outcome

An SRE was defined as a pathologic fracture (vertebral and non-vertebral), spinal cord compression, radiation to bone or surgery to bone.

Interventions

  • DRUG Placebo
  • DRUG Zoledronic acid

Trial Details

FieldValue
Enrollment Target 416 participants
Start Date 2006-02
Est. Completion 2013-07
Phase Phase 3
Novartis Pharmaceuticals

1,375 total trials

What the finished NCT00320710 record still lists

NCT00320710 is an interventional study that assigns participants to a tested intervention. The registered 416 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (46% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00320710 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00320710 about?

NCT00320710 is a clinical study titled "Continued Efficacy and Safety of Zoledronic Acid (q 4 Wks vs. q 12 Wks) in the 2nd Year of Treatment in Patients With Bone Metastases From Breast Cancer". Clinical trial in breast cancer patients with bone metastases pretreated for approximately 1 year with a standard zoledronic acid regimen. Looking at the continued effectiveness and safety of giving zoledronic acid every 4 weeks versus every 12 weeks given over 1 year. This study is prospective, dou...

What is the current status of trial NCT00320710?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 416 participants. The study started on 2006-02. Estimated completion is 2013-07.

What interventions are being tested in trial NCT00320710?

The interventions under investigation include: Placebo (DRUG), Zoledronic acid (DRUG).

Who is sponsoring clinical trial NCT00320710?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00320710's enrollment target sits among peer trials

416 902nd of 2000 higher than 1,098 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03527537 · 416 participants · Phase 4

    Gestational Diabetes and Pharmacotherapy (GAP)

  • NCT05007782 · 416 participants · Phase 1

    Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

  • NCT05520099 · 416 participants

    Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

  • NCT06075745 · 416 participants · Phase 2

    Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00320710, the US trial registry maintained by the National Library of Medicine. NCT00320710 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.