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NCT00315757 · ClinicalTrials.gov registry record · Phase 2

Study of Mapatumumab in Combination With Bortezomib (Velcade) and Bortezomib Alone in Subjects With Relapsed or Refractory Multiple Myeloma

A Phase 2 study, sponsored by Human Genome Sciences.

Completed
Registry status
Phase 2
Development phase
105
Enrollment target

NCT00315757: Completed Phase 2 study, sponsored by Human Genome Sciences.

NCT00315757 is a Phase 2 study that has completed, run by Human Genome Sciences. The registered enrollment target is 105 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (21% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00315757, a Phase 2 study, has completed, sponsored by Human Genome Sciences.

COMPLETED
Registry status
Phase 2
Development phase
105 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the efficacy (disease response) and safety of mapatumumab in combination with bortezomib and bortezomib alone in subjects with relapsed or refractory multiple myeloma (MM).

Interventions

  • DRUG Bortezomib
  • BIOLOGICAL Mapatumumab

Trial Details

FieldValue
Enrollment Target 105 participants
Start Date 2006-05
Est. Completion 2010-10
Phase Phase 2
Human Genome Sciences

17 total trials

What the finished NCT00315757 record still lists

NCT00315757 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (21% lower).

The record links to 0 conditions, and to 2 interventions - of which Bortezomib is the first listed.

NCT00315757 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00315757 about?

NCT00315757 is a clinical study titled "Study of Mapatumumab in Combination With Bortezomib (Velcade) and Bortezomib Alone in Subjects With Relapsed or Refractory Multiple Myeloma". The purpose of this study is to evaluate the efficacy (disease response) and safety of mapatumumab in combination with bortezomib and bortezomib alone in subjects with relapsed or refractory multiple myeloma (MM).

What is the current status of trial NCT00315757?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 105 participants. The study started on 2006-05. Estimated completion is 2010-10.

What interventions are being tested in trial NCT00315757?

The interventions under investigation include: Bortezomib (DRUG), Mapatumumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT00315757?

This trial is sponsored by Human Genome Sciences, which has 17 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00315757's enrollment target sits among peer trials

105 650th of 2000 higher than 1,341 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00315757, the US trial registry maintained by the National Library of Medicine. NCT00315757 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.