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NCT00315328 · ClinicalTrials.gov registry record · Phase 3
Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds
A Phase 3 study, sponsored by Jaeb Center for Health Research.
- Completed
- Registry status
- Phase 3
- Development phase
- 233
- Enrollment target
NCT00315328: Completed Phase 3 study, sponsored by Jaeb Center for Health Research.
NCT00315328 is a Phase 3 study that has completed, run by Jaeb Center for Health Research. The registered enrollment target is 233 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00315328, a Phase 3 study, has completed, sponsored by Jaeb Center for Health Research.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 233 participants
- Enrollment target
Study Summary
The purpose of this study is: * To compare the effectiveness of weekend atropine plus near activities and daily patching plus near activities for moderate amblyopia (20/40 to 20/100) and severe amblyopia (20/125 to 20/400) in improving vision in the amblyopic eye of 7 to \<13 year olds. * To determine the maximum improvement in vision of the amblyopic eye with each treatment. * To determine whether amblyopia is associated with structural abnormalities of optic nerve fiber layer.
Primary Outcome
Visual acuity was measured in each eye using the electronic early treatment diabetic retinopathy study (E-ETDRS) method which resulted in a letter score that could range from 0 to 97 letters, with 0 being the worst and 97 being the best.
Interventions
- DRUG Atropine
- DEVICE Patching
- PROCEDURE Near activities
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 233 participants |
| Start Date | 2005-08 |
| Est. Completion | 2008-01 |
| Phase | Phase 3 |
What the finished NCT00315328 record still lists
NCT00315328 is an interventional study that assigns participants to a tested intervention. The registered 233 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 3 interventions - of which Atropine is the first listed.
NCT00315328 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00315328 about?
NCT00315328 is a clinical study titled "Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds". The purpose of this study is: * To compare the effectiveness of weekend atropine plus near activities and daily patching plus near activities for moderate amblyopia (20/40 to 20/100) and severe amblyopia (20/125 to 20/400) in improving vision in the amblyopic eye of 7 to \<13 year olds. * To determ...
What is the current status of trial NCT00315328?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 233 participants. The study started on 2005-08. Estimated completion is 2008-01.
What interventions are being tested in trial NCT00315328?
The interventions under investigation include: Atropine (DRUG), Patching (DEVICE), Near activities (PROCEDURE).
Who is sponsoring clinical trial NCT00315328?
This trial is sponsored by Jaeb Center for Health Research, which has 119 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00315328's enrollment target sits among peer trials
233 1298th of 2000 higher than 703 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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