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NCT00307398 · ClinicalTrials.gov registry record · Phase 3

Anecortave Acetate Risk-Reduction Trial (AART)

A Phase 3 study, sponsored by Alcon Research.

Terminated
Registry status
Phase 3
Development phase
2,596
Enrollment target

NCT00307398: Clinical Trial Phase 3 study, sponsored by Alcon Research.

NCT00307398 is a Phase 3 study that was terminated before completion, run by Alcon Research. The registered enrollment target is 2,596 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (236% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00307398, a Phase 3 study, was terminated before completion, sponsored by Alcon Research.

TERMINATED
Registry status
Phase 3
Development phase
2,596 participants
Enrollment target

Study Summary

A 48 month study of posterior juxtascleral administrations of Anecortave Acetate 15 or 30 mg or sham administration every 6 months.

Primary Outcome

ST-CNV is defined as CNV or a portion of CNV within 2500 microns of the foveal center, as evidenced by digital angiography at the clinical site.

Interventions

  • OTHER Anecortave Acetate Vehicle
  • DRUG Anecortave Acetate (AL-3789) sterile suspension, 15 mg or 30 mg

Trial Details

FieldValue
Enrollment Target 2,596 participants
Start Date 2004-03
Est. Completion 2009-01
Phase Phase 3
Alcon Research

275 total trials

Why NCT00307398 stopped before completion

NCT00307398 is an interventional study that assigns participants to a tested intervention. Its 2,596 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (236% higher).

The record links to 0 conditions, and to 2 interventions - of which Anecortave Acetate Vehicle is the first listed.

NCT00307398 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00307398 about?

NCT00307398 is a clinical study titled "Anecortave Acetate Risk-Reduction Trial (AART)". A 48 month study of posterior juxtascleral administrations of Anecortave Acetate 15 or 30 mg or sham administration every 6 months.

What is the current status of trial NCT00307398?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 2,596 participants. The study started on 2004-03. Estimated completion is 2009-01.

What interventions are being tested in trial NCT00307398?

The interventions under investigation include: Anecortave Acetate Vehicle (OTHER), Anecortave Acetate (AL-3789) sterile suspension, 15 mg or 30 mg (DRUG).

Who is sponsoring clinical trial NCT00307398?

This trial is sponsored by Alcon Research, which has 275 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00307398's enrollment target sits among peer trials

2,596 85th of 2000 higher than 1,916 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00307398, the US trial registry maintained by the National Library of Medicine. NCT00307398 (large enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.