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NCT00306618 · ClinicalTrials.gov registry record · Phase 2

Safety and Efficacy Study of Panzem NCD to Treat Glioblastoma

A Phase 2 study, sponsored by CASI pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
27
Enrollment target

NCT00306618: Completed Phase 2 study, sponsored by CASI pharmaceuticals.

NCT00306618 is a Phase 2 study that has completed, run by CASI pharmaceuticals. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00306618, a Phase 2 study, has completed, sponsored by CASI pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
27 participants
Enrollment target

Study Summary

This single-center, open-label, phase 2 study will evaluate the anti-tumor activity, as well as the safety and pharmacokinetics, of Panzem (2-methoxyestradiol, 2ME2) Nanocrystal Colloidal Dispersion (NCD) administered in patients with recurrent glioblastoma multiforme (GBM)

Interventions

  • DRUG Panzem Nanocrystal Colloidal Dispersion

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2006-01
Est. Completion 2008-12
Phase Phase 2
CASI pharmaceuticals

11 total trials

What the finished NCT00306618 record still lists

NCT00306618 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 1 intervention - of which Panzem Nanocrystal Colloidal Dispersion is the first listed.

NCT00306618 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00306618 about?

NCT00306618 is a clinical study titled "Safety and Efficacy Study of Panzem NCD to Treat Glioblastoma". This single-center, open-label, phase 2 study will evaluate the anti-tumor activity, as well as the safety and pharmacokinetics, of Panzem (2-methoxyestradiol, 2ME2) Nanocrystal Colloidal Dispersion (NCD) administered in patients with recurrent glioblastoma multiforme (GBM)

What is the current status of trial NCT00306618?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2006-01. Estimated completion is 2008-12.

What interventions are being tested in trial NCT00306618?

The interventions under investigation include: Panzem Nanocrystal Colloidal Dispersion (DRUG).

Who is sponsoring clinical trial NCT00306618?

This trial is sponsored by CASI pharmaceuticals, which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00306618's enrollment target sits among peer trials

27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00306618, the US trial registry maintained by the National Library of Medicine. NCT00306618 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.