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NCT00305825 · ClinicalTrials.gov registry record · Phase 2
Bevacizumab and Letrozole in Treating Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer That Cannot Be Removed By Surgery
A Phase 2 study of Breast Cancer, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 2
- Development phase
- 43
- Enrollment target
- 2
- Study locations
NCT00305825: Completed Phase 2 study of Breast Cancer, sponsored by University of California, San Francisco.
NCT00305825 is a Phase 2 study of Breast Cancer that has completed, run by University of California, San Francisco. The registered enrollment target is 43 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00305825, a Phase 2 study of Breast Cancer, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 43 participants
- Enrollment target
- 2
- Study locations
Study Summary
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some find tumor cells and kill them or carry tumor-killing substances to them. Others interfere with the ability of tumor cells to grow and spread. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by lowering the amount of estrogen the body makes. Giving bevacizumab together with letrozole may be an effective treatment for locally advanced or metastatic breast cancer. PURPOSE: This phase II trial is studying how well giving bevacizumab together with letrozole works in treating postmenopausal women with locally advanced or metastatic breast cancer that cannot be removed by surgery.
Conditions Studied
Interventions
- DRUG letrozole
- BIOLOGICAL bevacizumab
Study Locations (2)
California
- UCSF Comprehensive Cancer Center - San Francisco
New York
- Memorial Sloan-Kettering Cancer Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2004-08 |
| Est. Completion | 2016-05-24 |
| Phase | Phase 2 |
What the finished NCT00305825 record still lists
NCT00305825 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which letrozole is the first listed.
NCT00305825 reports a single indexed study location in California, New York.
Frequently Asked Questions
What is clinical trial NCT00305825 about?
NCT00305825 is a clinical study titled "Bevacizumab and Letrozole in Treating Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer That Cannot Be Removed By Surgery". RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some find tumor cells and kill them or carry tumor-killing substances to them. Others interfere with the ability of tumor cells to grow and spread. Bevacizumab may also stop the growth of tumor cells by ...
What is the current status of trial NCT00305825?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2004-08. Estimated completion is 2016-05-24.
What conditions does trial NCT00305825 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT00305825?
The interventions under investigation include: letrozole (DRUG), bevacizumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT00305825?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00305825 being conducted?
This trial has 2 study locations across California, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00305825's enrollment target sits among peer trials
43 855th of 1224 higher than 362 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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