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NCT00303732 · ClinicalTrials.gov registry record · Phase 1

Vatalanib and Everolimus in Treating Patients With Advanced Solid Tumors

A Phase 1 study, sponsored by Daniel George, MD.

Completed
Registry status
Phase 1
Development phase
37
Enrollment target

NCT00303732: Completed Phase 1 study, sponsored by Daniel George, MD.

NCT00303732 is a Phase 1 study that has completed, run by Daniel George, MD. The registered enrollment target is 37 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (38% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00303732, a Phase 1 study, has completed, sponsored by Daniel George, MD.

COMPLETED
Registry status
Phase 1
Development phase
37 participants
Enrollment target

Study Summary

RATIONALE: Vatalanib and everolimus may stop the growth of tumor cells by blocking blood flow to the tumor and by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I trial is studying the side effects and best dose of vatalanib and everolimus and to see how well they work in treating patients with advanced solid tumors.

Primary Outcome

Patients were evaluated on Day 1,14 and 28 for dose limiting toxicities

Interventions

  • DRUG RAD001 (everolimus)
  • DRUG PTK787 (vatalanib)

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2004-12
Est. Completion 2012-08
Phase Phase 1
Daniel George, MD

6 total trials

What the finished NCT00303732 record still lists

NCT00303732 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (38% lower).

The record links to 0 conditions, and to 2 interventions - of which RAD001 (everolimus) is the first listed.

NCT00303732 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00303732 about?

NCT00303732 is a clinical study titled "Vatalanib and Everolimus in Treating Patients With Advanced Solid Tumors". RATIONALE: Vatalanib and everolimus may stop the growth of tumor cells by blocking blood flow to the tumor and by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I trial is studying the side effects and best dose of vatalanib and everolimus and to see how well they work in ...

What is the current status of trial NCT00303732?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2004-12. Estimated completion is 2012-08.

What interventions are being tested in trial NCT00303732?

The interventions under investigation include: RAD001 (everolimus) (DRUG), PTK787 (vatalanib) (DRUG).

Who is sponsoring clinical trial NCT00303732?

This trial is sponsored by Daniel George, MD, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00303732's enrollment target sits among peer trials

37 1204th of 2000 higher than 791 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00303732, the US trial registry maintained by the National Library of Medicine. NCT00303732 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.