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NCT00303134 · ClinicalTrials.gov registry record · Phase 1

Islet Cell Transplants for Diabetes

A Phase 1 study, sponsored by Weill Medical College of Cornell University.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT00303134: Clinical Trial Phase 1 study, sponsored by Weill Medical College of Cornell University.

NCT00303134 is a Phase 1 study that was terminated before completion, run by Weill Medical College of Cornell University. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00303134, a Phase 1 study, was terminated before completion, sponsored by Weill Medical College of Cornell University.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

The purpose of this study is to test the safety and efficacy of islet cell transplants for the treatment of type 1 diabetes mellitus. It has been shown that normal control of blood sugar levels can prevent progression of complications (such as kidney disease, nerve damage, and vascular disease) from diabetes. This research study is designed to see if normal blood sugar control can be achieved by transplanting pancreatic islet cells into your liver, which may reduce or eliminate your need for insulin. Patients may qualify to participate in this research study if they have type 1 diabetes mellitus for at least five years and meet at least one of the following criteria: * Experience hypoglycemic unawareness - Defined as inability to tell when blood glucose is low (for example, may not feel symptoms such as shaking, sweating, and rapid heartbeat that usually signify that glucose is low) * Have been hospitalized several times in the past year for low blood sugar and/or high blood sugar * Have complications of diabetes such as retinopathy, kidney problems, or neuropathy

Interventions

  • DRUG Islet Cell Transplantation

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2003-08-01
Est. Completion 2010-06-24
Phase Phase 1

Why NCT00303134 stopped before completion

NCT00303134 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 1 intervention - of which Islet Cell Transplantation is the first listed.

NCT00303134 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00303134 about?

NCT00303134 is a clinical study titled "Islet Cell Transplants for Diabetes". The purpose of this study is to test the safety and efficacy of islet cell transplants for the treatment of type 1 diabetes mellitus. It has been shown that normal control of blood sugar levels can prevent progression of complications (such as kidney disease, nerve damage, and vascular disease) from...

What is the current status of trial NCT00303134?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2003-08-01. Estimated completion is 2010-06-24.

What interventions are being tested in trial NCT00303134?

The interventions under investigation include: Islet Cell Transplantation (DRUG).

Who is sponsoring clinical trial NCT00303134?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00303134's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00303134, the US trial registry maintained by the National Library of Medicine. NCT00303134 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.