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NCT00302068 · ClinicalTrials.gov registry record · Phase 3
Exercise to Treat Depression in Individuals With Coronary Heart Disease
A Phase 3 study, sponsored by Duke University.
- Completed
- Registry status
- Phase 3
- Development phase
- 101
- Enrollment target
NCT00302068: Completed Phase 3 study, sponsored by Duke University.
NCT00302068 is a Phase 3 study that has completed, run by Duke University. The registered enrollment target is 101 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00302068, a Phase 3 study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 101 participants
- Enrollment target
Study Summary
Some individuals with coronary heart disease (CHD) suffer from depression and use antidepressant medications to reduce symptoms. However, preliminary research has shown that exercise may be a more effective way to treat depression in these individuals. The purpose of this study is to evaluate the effects of exercise in reducing depression and improving heart function in individuals with CHD.
Primary Outcome
The Hamilton Depression Rating Scale ranges from 0 to 52, with lower scores reflecting lower levels of depression and higher scores greater severity of depression.
Interventions
- DRUG Sertraline
- BEHAVIORAL Supervised Aerobic Exercise
- DRUG Placebo Pill.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2006-07 |
| Est. Completion | 2011-12 |
| Phase | Phase 3 |
What the finished NCT00302068 record still lists
NCT00302068 is an interventional study that assigns participants to a tested intervention. The registered 101 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 3 interventions - of which Sertraline is the first listed.
NCT00302068 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00302068 about?
NCT00302068 is a clinical study titled "Exercise to Treat Depression in Individuals With Coronary Heart Disease". Some individuals with coronary heart disease (CHD) suffer from depression and use antidepressant medications to reduce symptoms. However, preliminary research has shown that exercise may be a more effective way to treat depression in these individuals. The purpose of this study is to evaluate the ef...
What is the current status of trial NCT00302068?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 101 participants. The study started on 2006-07. Estimated completion is 2011-12.
What interventions are being tested in trial NCT00302068?
The interventions under investigation include: Sertraline (DRUG), Supervised Aerobic Exercise (BEHAVIORAL), Placebo Pill. (DRUG).
Who is sponsoring clinical trial NCT00302068?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00302068's enrollment target sits among peer trials
101 1680th of 2000 higher than 320 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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