Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00298285 · ClinicalTrials.gov registry record · Phase 4

ABRIDGE: Low Molecular Weight Heparin in Bridging Patients After Mechanical Valve Replacement

A Phase 4 study of Mechanical Valve Replacement and Warfarin Therapy, sponsored by The Cleveland Clinic.

Completed
Registry status
Phase 4
Development phase
100
Enrollment target
1
Study location

NCT00298285: Completed Phase 4 study of Mechanical Valve Replacement and Warfarin Therapy, sponsored by The Cleveland Clinic.

NCT00298285 is a Phase 4 study of Mechanical Valve Replacement and Warfarin Therapy that has completed, run by The Cleveland Clinic. The registered enrollment target is 100 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00298285, a Phase 4 study of Mechanical Valve Replacement and Warfarin Therapy, has completed, sponsored by The Cleveland Clinic.

COMPLETED
Registry status
Phase 4
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

The primary aim is to determine the rate of major bleeding and blood clots when using enoxaparin as a bridge to oral blood thinning medication in patients who have undergone mechanical valve replacement.

Interventions

  • DRUG enoxaparin

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 100 participants
Est. Completion 2006-10
Phase Phase 4
The Cleveland Clinic

688 total trials

What the finished NCT00298285 record still lists

NCT00298285 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower).

The record links to 2 conditions, with Mechanical Valve Replacement appearing as the primary indexed condition, and to 1 intervention - of which enoxaparin is the first listed.

NCT00298285 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT00298285 about?

NCT00298285 is a clinical study titled "ABRIDGE: Low Molecular Weight Heparin in Bridging Patients After Mechanical Valve Replacement". The primary aim is to determine the rate of major bleeding and blood clots when using enoxaparin as a bridge to oral blood thinning medication in patients who have undergone mechanical valve replacement.

What is the current status of trial NCT00298285?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 100 participants. Estimated completion is 2006-10.

What conditions does trial NCT00298285 study?

This clinical trial studies the following conditions: Mechanical Valve Replacement, Warfarin Therapy.

What interventions are being tested in trial NCT00298285?

The interventions under investigation include: enoxaparin (DRUG).

Who is sponsoring clinical trial NCT00298285?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00298285 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT00298285's enrollment target sits among peer trials

100 770th of 2000 higher than 1,149 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01048281 · 100 participants

    Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

  • NCT01161199 · 100 participants

    The Use of Leukapheresis to Support HIV Pathogenesis Studies

  • NCT01327690 · 100 participants · Early Phase 1

    Mental Health in Veterans and Families After Group Therapies

  • NCT01730781 · 100 participants

    Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Source: ClinicalTrials.gov NCT00298285, the US trial registry maintained by the National Library of Medicine. NCT00298285 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.