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NCT00296400 · ClinicalTrials.gov registry record · Phase 2

Prospective Evaluation of Proteinuria and Renal Function in Non-diabetic Patients With Progressive Renal Disease

A Phase 2 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 2
Development phase
237
Enrollment target

NCT00296400: Completed Phase 2 study, sponsored by AstraZeneca.

NCT00296400 is a Phase 2 study that has completed, run by AstraZeneca. The registered enrollment target is 237 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00296400, a Phase 2 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 2
Development phase
237 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the effects of Crestor (rosuvastatin) and (Lipitor) atorvastatin on urinary protein excretion over 1 year in non-diabetes with moderate proteinuria and hypercholesterolaemia.

Primary Outcome

Urinary protein/creatinine ratio (mg/g) =urine protein concentration (mg/dL)/ urine creatinine concentration (g/dL). Outcome measure is the ratio of Week 52 \[LOCF\] urine protein/creatinine ratio over baseline urine protein/creatinine ratio.

Interventions

  • DRUG Rosuvastatin
  • DRUG Atorvastatin

Trial Details

FieldValue
Enrollment Target 237 participants
Start Date 2006-02
Est. Completion 2009-06
Phase Phase 2
AstraZeneca

1,285 total trials

What the finished NCT00296400 record still lists

NCT00296400 is an interventional study that assigns participants to a tested intervention. The registered 237 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% higher).

The record links to 0 conditions, and to 2 interventions - of which Rosuvastatin is the first listed.

NCT00296400 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00296400 about?

NCT00296400 is a clinical study titled "Prospective Evaluation of Proteinuria and Renal Function in Non-diabetic Patients With Progressive Renal Disease". The purpose of this study is to evaluate the effects of Crestor (rosuvastatin) and (Lipitor) atorvastatin on urinary protein excretion over 1 year in non-diabetes with moderate proteinuria and hypercholesterolaemia.

What is the current status of trial NCT00296400?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 237 participants. The study started on 2006-02. Estimated completion is 2009-06.

What interventions are being tested in trial NCT00296400?

The interventions under investigation include: Rosuvastatin (DRUG), Atorvastatin (DRUG).

Who is sponsoring clinical trial NCT00296400?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00296400's enrollment target sits among peer trials

237 255th of 2000 higher than 1,746 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00296400, the US trial registry maintained by the National Library of Medicine. NCT00296400 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.