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NCT00294190 · ClinicalTrials.gov registry record · Phase 2

Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancer

A Phase 2 study of Small-cell Lung Cancer and Carcinoma, Small Cell, sponsored by SCRI Development Innovations.

Completed
Registry status
Phase 2
Development phase
38
Enrollment target
13
Study locations

NCT00294190 is a Phase 2 study of Small-cell Lung Cancer and Carcinoma, Small Cell that has completed, run by SCRI Development Innovations. The registered enrollment target is 38 participants, below the 232-participant average among 79 other Small-cell Lung Cancer trials with a reported enrollment target (84% lower). The trial reports 13 study locations across 10 states.

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The verdict

NCT00294190, a Phase 2 study of Small-cell Lung Cancer and Carcinoma, Small Cell, has completed, sponsored by SCRI Development Innovations.

COMPLETED
Registry status
Phase 2
Development phase
38 participants
Enrollment target
13
Study locations

Study Summary

This proposed phase II trial will investigate weekly topotecan at a higher dose than was used in the previous trials in an attempt to achieve improved response rates and disease control without added toxicity. To help ameliorate the fatigue, planned rest weeks will be incorporated into the schedule. This trial will be the first clinical trial to evaluate a higher dose of weekly topotecan in the treatment of extensive-stage SCLC.

Interventions

  • DRUG Topotecan

Study Locations (13)

Florida

  • Florida Cancer Specialists - Fort Myers
  • Watson Clinic Center for Cancer Care and Research - Lakeland
  • Florida Hospital Cancer Institute - Orlando

Tennessee

  • Chattanooga Oncology Hematology Associates - Chattanooga
  • Tennessee Oncology, PLLC - Nashville

Arkansas

  • Northeast Arkansas Clinic - Jonesboro

Georgia

  • Northeast Georgia Medical Center - Gainesville

Kentucky

  • Consultants in Blood Disorders and Cancer - Louisville

Louisiana

  • Hematology Oncology Life Center - Alexandria

Michigan

  • Grand Rapids Clinical Oncology Program - Grand Rapids

Nebraska

  • Methodist Cancer Center - Omaha

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2006-02
Est. Completion 2009-07
Phase Phase 2

Sponsor

SCRI Development Innovations

146 total trials

What the Registry Record Tells You About NCT00294190

The ClinicalTrials.gov registry entry for NCT00294190 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 232-participant average among 79 other Small-cell Lung Cancer trials with a reported enrollment target (84% lower). The listed sponsor is SCRI Development Innovations, which has 146 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Small-cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which Topotecan is the first listed.

NCT00294190 reports 13 study locations spanning 10 distinct geographic areas - top geographies include Florida, Tennessee, Arkansas.

Frequently Asked Questions

What is clinical trial NCT00294190 about?

NCT00294190 is a clinical study titled "Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancer". This proposed phase II trial will investigate weekly topotecan at a higher dose than was used in the previous trials in an attempt to achieve improved response rates and disease control without added toxicity. To help ameliorate the fatigue, planned rest weeks will be incorporated into the schedule....

What is the current status of trial NCT00294190?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 38 participants. The study started on 2006-02. Estimated completion is 2009-07.

What conditions does trial NCT00294190 study?

This clinical trial studies the following conditions: Small-cell Lung Cancer, Carcinoma, Small Cell.

What interventions are being tested in trial NCT00294190?

The interventions under investigation include: Topotecan (DRUG).

Who is sponsoring clinical trial NCT00294190?

This trial is sponsored by SCRI Development Innovations, which has 146 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00294190 being conducted?

This trial has 13 study locations across Arkansas, Florida, Georgia, Kentucky, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.