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NCT00294021 · ClinicalTrials.gov registry record

Long-term Impact of Pneumococcal Conjugate Vaccine on Carriage

A clinical trial, sponsored by Johns Hopkins Bloomberg School of Public Health.

Completed
Registry status
1,000
Enrollment target

NCT00294021 is a clinical trial that has completed, run by Johns Hopkins Bloomberg School of Public Health. The registered enrollment target is 1,000 participants.

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The verdict

NCT00294021 has completed, sponsored by Johns Hopkins Bloomberg School of Public Health.

COMPLETED
Registry status
1,000 participants
Enrollment target

Study Summary

Pneumococcus is a major cause of morbidity and mortality. In 2000, a pneumococcal conjugate vaccine (PCV) was licensed for use in children and is now part of the routine childhood vaccine schedule. PCV is known to reduce invasive disease and protect against nasopharyngeal (NP) acquisition of vaccine serotype pneumococci; it also results in an increased risk of nonvaccine serotype carriage. This study proposes to assess the longterm impact of vaccine on NP carriage in a setting where there is intense antibody pressure on the ecology of the pneumococcus. A cross sectional study of pneumococcal NP colonization among American Indian children will be combined with surveillance for invasive disease in the same population. The purpose is to determine the impact of community wide PCV use on NP colonization and the relationship with invasive disease. This longterm safety issue needs to be assessed to fully evaluate the impact of vaccine on NP ecology and invasive disease.

Trial Details

FieldValue
Enrollment Target 1,000 participants
Start Date 2006-03
Est. Completion 2008-04

What the Registry Record Tells You About NCT00294021

The ClinicalTrials.gov registry entry for NCT00294021 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins Bloomberg School of Public Health, which has 187 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT00294021 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00294021 about?

NCT00294021 is a clinical study titled "Long-term Impact of Pneumococcal Conjugate Vaccine on Carriage". Pneumococcus is a major cause of morbidity and mortality. In 2000, a pneumococcal conjugate vaccine (PCV) was licensed for use in children and is now part of the routine childhood vaccine schedule. PCV is known to reduce invasive disease and protect against nasopharyngeal (NP) acquisition of vaccine...

What is the current status of trial NCT00294021?

This trial is currently completed. The enrollment target is 1,000 participants. The study started on 2006-03. Estimated completion is 2008-04.

Who is sponsoring clinical trial NCT00294021?

This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 187 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.