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NCT00290290 · ClinicalTrials.gov registry record · Phase 3
Efficacy Study of Antiseptic Preoperative Scrubs in Prevention of Postoperative Infections
A Phase 3 study, sponsored by Baylor College of Medicine.
- Completed
- Registry status
- Phase 3
- Development phase
- 849
- Enrollment target
NCT00290290: Completed Phase 3 study, sponsored by Baylor College of Medicine.
NCT00290290 is a Phase 3 study that has completed, run by Baylor College of Medicine. The registered enrollment target is 849 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (10% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00290290, a Phase 3 study, has completed, sponsored by Baylor College of Medicine.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 849 participants
- Enrollment target
Study Summary
Most cases of infection of clean-contaminated wounds (wounds without gross spillage of organisms from the gastrointestinal tract) are thought to originate from the skin. Therefore, it is conceivable that application of an optimal antiseptic agent can reduce the rate of surgical wound infections. This trial is to compare the impact of disinfecting the skin with Chloraprep (2%chlorhexidine and 70% isopropyl alcohol) vs. Betadine on the rates of infection of clean-contaminated surgical wounds. The study will also assess the occurrence of adverse effects on the skin from either antiseptic agent and the cost-savings associated with the use of Chloraprep vs Betadine.
Primary Outcome
The primary end point of the study was the occurrence of any surgical-site infection. Diagnosis of surgical-site infection was diagnosed by a blinded reviewer following criteria developed by the Center for Disease Control. The significance of difference between the two study groups in terms of patient characteristics was determined with the use of the Wilcoxon rank-sum test for continuous variables and Fisher's exact test for categorical variables. For efficacy outcomes, we compared the proporti
Interventions
- DRUG Povidone-Iodine
- DRUG chlorhexidine-alcohol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 849 participants |
| Start Date | 2003-09 |
| Est. Completion | 2008-05 |
| Phase | Phase 3 |
What the finished NCT00290290 record still lists
NCT00290290 is an interventional study that assigns participants to a tested intervention. The registered 849 participants enrollment target is mid-sized for trials with a published cap, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (10% higher).
The record links to 0 conditions, and to 2 interventions - of which Povidone-Iodine is the first listed.
NCT00290290 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00290290 about?
NCT00290290 is a clinical study titled "Efficacy Study of Antiseptic Preoperative Scrubs in Prevention of Postoperative Infections". Most cases of infection of clean-contaminated wounds (wounds without gross spillage of organisms from the gastrointestinal tract) are thought to originate from the skin. Therefore, it is conceivable that application of an optimal antiseptic agent can reduce the rate of surgical wound infections. Thi...
What is the current status of trial NCT00290290?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 849 participants. The study started on 2003-09. Estimated completion is 2008-05.
What interventions are being tested in trial NCT00290290?
The interventions under investigation include: Povidone-Iodine (DRUG), chlorhexidine-alcohol (DRUG).
Who is sponsoring clinical trial NCT00290290?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00290290's enrollment target sits among peer trials
849 389th of 2000 higher than 1,612 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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