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NCT00289601 · ClinicalTrials.gov registry record · Phase 4
Randomized Study of Aspirin Resistant Patients Undergoing Angioplasty
A Phase 4 study, sponsored by Brigham and Women's Hospital.
- Terminated
- Registry status
- Phase 4
- Development phase
- 1,200
- Enrollment target
NCT00289601: Clinical Trial Phase 4 study, sponsored by Brigham and Women's Hospital.
NCT00289601 is a Phase 4 study that was terminated before completion, run by Brigham and Women's Hospital. The registered enrollment target is 1,200 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (132% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00289601, a Phase 4 study, was terminated before completion, sponsored by Brigham and Women's Hospital.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 1,200 participants
- Enrollment target
Study Summary
This study is a randomized, double-blind, multi-center study designed to compare differences in rates of myonecrosis (measured as an elevation of CK-MB ratio ≥ 2 times ULN) within 24 hours following low-medium risk percutaneous coronary intervention (PCI) in aspirin or clopidogrel non-responsive patients who are randomized to heparin with or without eptifibatide therapy during PCI. The primary objective of this study is to determine if the use of eptifibatide is associated with a significant difference in post-PCI myonecrosis (measured as an elevation of CK-MB ratio ≥ 2 times upper limit of normal \[ULN\]) within 24 hours of low-medium risk PCI in patients who are aspirin or non-responsive as determined by VerifyNow Aspirin and P2Y12 testing.
Interventions
- DRUG eptifibatide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,200 participants |
| Start Date | 2006-03 |
| Est. Completion | 2007-12 |
| Phase | Phase 4 |
Why NCT00289601 stopped before completion
NCT00289601 is an interventional study that assigns participants to a tested intervention. Its 1,200 participants enrollment target places it among the larger protocols in the corpus, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (132% higher).
The record links to 0 conditions, and to 1 intervention - of which eptifibatide is the first listed.
NCT00289601 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00289601 about?
NCT00289601 is a clinical study titled "Randomized Study of Aspirin Resistant Patients Undergoing Angioplasty". This study is a randomized, double-blind, multi-center study designed to compare differences in rates of myonecrosis (measured as an elevation of CK-MB ratio ≥ 2 times ULN) within 24 hours following low-medium risk percutaneous coronary intervention (PCI) in aspirin or clopidogrel non-responsive pat...
What is the current status of trial NCT00289601?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 1,200 participants. The study started on 2006-03. Estimated completion is 2007-12.
What interventions are being tested in trial NCT00289601?
The interventions under investigation include: eptifibatide (DRUG).
Who is sponsoring clinical trial NCT00289601?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00289601's enrollment target sits among peer trials
1,200 62nd of 2000 higher than 1,938 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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