Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00284128 · ClinicalTrials.gov registry record · Phase 2
AVE7688 in Patients With Mild to Moderate Blood Pressure
A Phase 2 study, sponsored by Sanofi.
- Completed
- Registry status
- Phase 2
- Development phase
- 1,940
- Enrollment target
NCT00284128: Completed Phase 2 study, sponsored by Sanofi.
NCT00284128 is a Phase 2 study that has completed, run by Sanofi. The registered enrollment target is 1,940 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (1359% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00284128, a Phase 2 study, has completed, sponsored by Sanofi.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 1,940 participants
- Enrollment target
Study Summary
The primary objective is to assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough diastolic blood pressure at the end of week 12. The secondary objectives are: * To assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough systolic blood pressure at the end of week 12 * To compare the percentages of responders after 12 week of treatment * To evaluate the long term safety and tolerability of AVE 7688 with particular attention to angioedema
Interventions
- DRUG AVE7688
- DRUG Losartan-potassium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,940 participants |
| Start Date | 2005-12 |
| Est. Completion | 2008-03 |
| Phase | Phase 2 |
What the finished NCT00284128 record still lists
NCT00284128 is an interventional study that assigns participants to a tested intervention. Its 1,940 participants enrollment target places it among the larger protocols in the corpus, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (1359% higher).
The record links to 0 conditions, and to 2 interventions - of which AVE7688 is the first listed.
NCT00284128 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00284128 about?
NCT00284128 is a clinical study titled "AVE7688 in Patients With Mild to Moderate Blood Pressure". The primary objective is to assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough diastolic blood pressure at the end of week 12. The secondary objectives are: * To assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change f...
What is the current status of trial NCT00284128?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 1,940 participants. The study started on 2005-12. Estimated completion is 2008-03.
What interventions are being tested in trial NCT00284128?
The interventions under investigation include: AVE7688 (DRUG), Losartan-potassium (DRUG).
Who is sponsoring clinical trial NCT00284128?
This trial is sponsored by Sanofi, which has 713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00284128's enrollment target sits among peer trials
1,940 9th of 2000 higher than 1,992 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT05233150 · 1,932 participants · NA
Child-Adult Relationship Enhancement in Primary Care (PriCARE) / Criando Niños Con CARIÑO (CARIÑO)
- NCT04251052 · 1,956 participants · NA
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
- NCT06058455 · 1,920 participants · NA
An Evaluation of an Online Sexual Assault Resistance Program (IDEA3)
- NCT05174169 · 1,912 participants · Phase 2
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia