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NCT00283114 · ClinicalTrials.gov registry record · Phase 1

A Safety Study of Lintuzumab in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome

A Phase 1 study, sponsored by Seagen.

Completed
Registry status
Phase 1
Development phase
82
Enrollment target

NCT00283114 is a Phase 1 study that has completed, run by Seagen. The registered enrollment target is 82 participants.

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The verdict

NCT00283114, a Phase 1 study, has completed, sponsored by Seagen.

COMPLETED
Registry status
Phase 1
Development phase
82 participants
Enrollment target

Study Summary

Phase 1a is an open-label, multi-dose, single-arm, dose-escalation study to define the toxicity profile, pharmacokinetics, and antitumor activity of SGN-33 in patients with myelodysplastic syndrome (MDS), acute myelogenous leukemia(AML), and CD33+ myeloproliferative diseases. Phase 1b includes patients with AML or MDS treated at the highest tolerated dose from phase 1a.

Interventions

  • DRUG lintuzumab

Trial Details

FieldValue
Enrollment Target 82 participants
Start Date 2005-11
Est. Completion 2010-01
Phase Phase 1

Sponsor

Seagen

84 total trials

What the Registry Record Tells You About NCT00283114

The ClinicalTrials.gov registry entry for NCT00283114 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 82 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Seagen, which has 84 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which lintuzumab is the first listed.

NCT00283114 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00283114 about?

NCT00283114 is a clinical study titled "A Safety Study of Lintuzumab in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome". Phase 1a is an open-label, multi-dose, single-arm, dose-escalation study to define the toxicity profile, pharmacokinetics, and antitumor activity of SGN-33 in patients with myelodysplastic syndrome (MDS), acute myelogenous leukemia(AML), and CD33+ myeloproliferative diseases. Phase 1b includes patie...

What is the current status of trial NCT00283114?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 82 participants. The study started on 2005-11. Estimated completion is 2010-01.

What interventions are being tested in trial NCT00283114?

The interventions under investigation include: lintuzumab (DRUG).

Who is sponsoring clinical trial NCT00283114?

This trial is sponsored by Seagen, which has 84 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.