Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00282464 · ClinicalTrials.gov registry record · Phase 3

A Six-week Flexible Dose Study Evaluating the Efficacy and Safety of Geodon in Patients With Bipolar I Depression.

A Phase 3 study, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.

Completed
Registry status
Phase 3
Development phase
392
Enrollment target

NCT00282464: Completed Phase 3 study, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.

NCT00282464 is a Phase 3 study that has completed, run by Pfizer's Upjohn has merged with Mylan to form Viatris. The registered enrollment target is 392 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (49% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00282464, a Phase 3 study, has completed, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.

COMPLETED
Registry status
Phase 3
Development phase
392 participants
Enrollment target

Study Summary

This is a 6-week trial that evaluates the efficacy and safety of Geodon (ziprasidone) in outpatient subjects ages 18 and older with Bipolar Disorder type I, depressed. Subjects are required to undergo a washout period of at least 7 days of any prior med.

Primary Outcome

Change is observed value at each visit minus baseline value. MADRS:10-item instrument measuring depression; scale range between 0(Normal) - 6(most abnormal)for each item. Total possible score is 0 - 60. Overall is average response Week 1 - Week 6.

Interventions

  • DRUG Placebo
  • DRUG Geodon (Ziprasidone)

Trial Details

FieldValue
Enrollment Target 392 participants
Start Date 2006-02
Est. Completion 2008-03
Phase Phase 3

What the finished NCT00282464 record still lists

NCT00282464 is an interventional study that assigns participants to a tested intervention. The registered 392 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (49% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00282464 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00282464 about?

NCT00282464 is a clinical study titled "A Six-week Flexible Dose Study Evaluating the Efficacy and Safety of Geodon in Patients With Bipolar I Depression.". This is a 6-week trial that evaluates the efficacy and safety of Geodon (ziprasidone) in outpatient subjects ages 18 and older with Bipolar Disorder type I, depressed. Subjects are required to undergo a washout period of at least 7 days of any prior med.

What is the current status of trial NCT00282464?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 392 participants. The study started on 2006-02. Estimated completion is 2008-03.

What interventions are being tested in trial NCT00282464?

The interventions under investigation include: Placebo (DRUG), Geodon (Ziprasidone) (DRUG).

Who is sponsoring clinical trial NCT00282464?

This trial is sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris, which has 158 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00282464's enrollment target sits among peer trials

392 967th of 2000 higher than 1,033 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06397703 · 392 participants · Phase 2

    ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer

  • NCT06625775 · 392 participants · Phase 1

    Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

  • NCT07220967 · 392 participants · Phase 4

    A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement

  • NCT07290036 · 392 participants · Phase 1

    A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00282464, the US trial registry maintained by the National Library of Medicine. NCT00282464 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.