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NCT00280839 · ClinicalTrials.gov registry record · Phase 3

Safety and Efficacy Study of Topiramate to Aid in Smoking Cessation

A Phase 3 study of Smoking Cessation, sponsored by Lindner Center of HOPE.

Completed
Registry status
Phase 3
Development phase
87
Enrollment target
1
Study location

NCT00280839: Completed Phase 3 study of Smoking Cessation, sponsored by Lindner Center of HOPE.

NCT00280839 is a Phase 3 study of Smoking Cessation that has completed, run by Lindner Center of HOPE. The registered enrollment target is 87 participants, below the 474-participant average among 188 other Smoking Cessation trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00280839, a Phase 3 study of Smoking Cessation, has completed, sponsored by Lindner Center of HOPE.

COMPLETED
Registry status
Phase 3
Development phase
87 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research study is to determine if topiramate is safe and effective in the treatment of smoking cessation

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Topiramate

Study Locations (1)

Ohio

  • University of Cincinnati Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 87 participants
Phase Phase 3
Lindner Center of HOPE

23 total trials

What the finished NCT00280839 record still lists

NCT00280839 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 87 participants, a relatively small participant target, below the 474-participant average among 188 other Smoking Cessation trials with a reported enrollment target (82% lower).

The record links to 1 condition, with Smoking Cessation appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00280839 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT00280839 about?

NCT00280839 is a clinical study titled "Safety and Efficacy Study of Topiramate to Aid in Smoking Cessation". The purpose of this research study is to determine if topiramate is safe and effective in the treatment of smoking cessation

What is the current status of trial NCT00280839?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 87 participants.

What conditions does trial NCT00280839 study?

This clinical trial studies the following conditions: Smoking Cessation.

What interventions are being tested in trial NCT00280839?

The interventions under investigation include: Placebo (DRUG), Topiramate (DRUG).

Who is sponsoring clinical trial NCT00280839?

This trial is sponsored by Lindner Center of HOPE, which has 23 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00280839 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Smoking Cessation

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00280839's enrollment target sits among peer trials

87 123rd of 188 higher than 66 of 188 other Smoking Cessation trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Smoking Cessation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

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Source: ClinicalTrials.gov NCT00280839, the US trial registry maintained by the National Library of Medicine. NCT00280839 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.