Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00280540 · ClinicalTrials.gov registry record · Phase 4
Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Therapy in Patients With Hypertension
A Phase 4 study, sponsored by Novartis.
- Completed
- Registry status
- Phase 4
- Development phase
- 648
- Enrollment target
NCT00280540: Completed Phase 4 study, sponsored by Novartis.
NCT00280540 is a Phase 4 study that has completed, run by Novartis. The registered enrollment target is 648 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (25% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00280540, a Phase 4 study, has completed, sponsored by Novartis.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 648 participants
- Enrollment target
Study Summary
This is a double-blind study to evaluate the reduction in systolic blood pressure using a therapy initiated with valsartan 160 mg or valsartan + hydrochlorothiazide (HCTZ) 160/12.5 mg compared to a more conventional approach (therapy initiated with low-dose valsartan 80 mg).
Interventions
- DRUG Valsartan/Hydrochlorothiazide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 648 participants |
| Start Date | 2005-12 |
| Phase | Phase 4 |
What the finished NCT00280540 record still lists
NCT00280540 is an interventional study that assigns participants to a tested intervention. The registered 648 participants enrollment target is mid-sized for trials with a published cap, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (25% higher).
The record links to 0 conditions, and to 1 intervention - of which Valsartan/Hydrochlorothiazide is the first listed.
NCT00280540 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00280540 about?
NCT00280540 is a clinical study titled "Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Therapy in Patients With Hypertension". This is a double-blind study to evaluate the reduction in systolic blood pressure using a therapy initiated with valsartan 160 mg or valsartan + hydrochlorothiazide (HCTZ) 160/12.5 mg compared to a more conventional approach (therapy initiated with low-dose valsartan 80 mg).
What is the current status of trial NCT00280540?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 648 participants. The study started on 2005-12.
What interventions are being tested in trial NCT00280540?
The interventions under investigation include: Valsartan/Hydrochlorothiazide (DRUG).
Who is sponsoring clinical trial NCT00280540?
This trial is sponsored by Novartis, which has 265 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00280540's enrollment target sits among peer trials
648 124th of 2000 higher than 1,877 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT07027306 · 648 participants
The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures
- NCT07164456 · 648 participants · NA
Together Stronger: A Family-centered Lifestyle Intervention for Black Prostate Cancer Survivors and Their Caregivers
- NCT02934477 · 650 participants
Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis
- NCT04579120 · 650 participants
Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia