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NCT00275262 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate the Ability of Lupron Depot to Enhance Immune Function Following Bone Marrow Transplantation

A Phase 2 study, sponsored by Abbott.

Terminated
Registry status
Phase 2
Development phase
25
Enrollment target

NCT00275262: Clinical Trial Phase 2 study, sponsored by Abbott.

NCT00275262 is a Phase 2 study that was terminated before completion, run by Abbott. The registered enrollment target is 25 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00275262, a Phase 2 study, was terminated before completion, sponsored by Abbott.

TERMINATED
Registry status
Phase 2
Development phase
25 participants
Enrollment target

Study Summary

Phase 2 study, conducted in patients with Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, or mantle cell lymphoma undergoing high-dose chemotherapy and autologous stem cell transplantation.

Primary Outcome

Patients received a subcutaneous injection of KLH vaccine 1 month after subjects received the third injection of LAD or placebo. Serum immunoglobulin IgM antibodies were determined by enzyme-linked immunosorbent assay (ELISA). Baseline is defined as the IgM concentration before the KLH vaccination. Change from baseline was calculated as the IgM value postvaccination minus the IgM value at prevaccination.

Interventions

  • DRUG Matched placebo
  • DRUG Leuprolide acetate depot (LAD) 11.25 mg 3 Month

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2006-02
Phase Phase 2
Abbott

181 total trials

Why NCT00275262 stopped before completion

NCT00275262 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower).

The record links to 0 conditions, and to 2 interventions - of which Matched placebo is the first listed.

NCT00275262 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00275262 about?

NCT00275262 is a clinical study titled "A Study to Evaluate the Ability of Lupron Depot to Enhance Immune Function Following Bone Marrow Transplantation". Phase 2 study, conducted in patients with Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, or mantle cell lymphoma undergoing high-dose chemotherapy and autologous stem cell transplantation.

What is the current status of trial NCT00275262?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2006-02.

What interventions are being tested in trial NCT00275262?

The interventions under investigation include: Matched placebo (DRUG), Leuprolide acetate depot (LAD) 11.25 mg 3 Month (DRUG).

Who is sponsoring clinical trial NCT00275262?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00275262's enrollment target sits among peer trials

25 1719th of 2000 higher than 245 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00275262, the US trial registry maintained by the National Library of Medicine. NCT00275262 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.