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NCT00274794 · ClinicalTrials.gov registry record · NA

VP and G-CSF With or Without Rituximab in Autologous Peripheral Stem Cell Transplant For NHL

A NA study, sponsored by The Cleveland Clinic.

Completed
Registry status
NA
Development phase
55
Enrollment target

NCT00274794: Completed NA study, sponsored by The Cleveland Clinic.

NCT00274794 is a NA study that has completed, run by The Cleveland Clinic. The registered enrollment target is 55 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00274794, a NA study, has completed, sponsored by The Cleveland Clinic.

COMPLETED
Registry status
NA
Development phase
55 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as busulfan, etoposide, and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving colony-stimulating factors, such as G-CSF, monoclonal antibodies, such as rituximab, or chemotherapy, such as etoposide, helps stem cells move from the bone marrow to the blood so they can be collected and stored until transplant. Giving etoposide and G-CSF together with rituximab before a peripheral stem cell transplant may be an effective treatment for non-Hodgkin's lymphoma. PURPOSE: This randomized clinical trial is studying how well giving etoposide and G-CSF with or without rituximab works in treating patients who are undergoing an autologous peripheral stem cell transplant for B-cell non-Hodgkin's lymphoma.

Interventions

  • BIOLOGICAL rituximab
  • BIOLOGICAL filgrastim

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2000-02
Est. Completion 2006-05
Phase NA
The Cleveland Clinic

688 total trials

What the finished NCT00274794 record still lists

NCT00274794 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which rituximab is the first listed.

NCT00274794 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00274794 about?

NCT00274794 is a clinical study titled "VP and G-CSF With or Without Rituximab in Autologous Peripheral Stem Cell Transplant For NHL". RATIONALE: Drugs used in chemotherapy, such as busulfan, etoposide, and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving colony-stimulating factors, such as G-CSF, monoclonal antibodies, such as rituxim...

What is the current status of trial NCT00274794?

This trial is currently completed. It is a NA study. The enrollment target is 55 participants. The study started on 2000-02. Estimated completion is 2006-05.

What interventions are being tested in trial NCT00274794?

The interventions under investigation include: rituximab (BIOLOGICAL), filgrastim (BIOLOGICAL).

Who is sponsoring clinical trial NCT00274794?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00274794's enrollment target sits among peer trials

55 1264th of 2000 higher than 733 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00274794, the US trial registry maintained by the National Library of Medicine. NCT00274794 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.