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NCT00267371 · ClinicalTrials.gov registry record · Phase 3
ESCAPE Migraine Trial
A Phase 3 study, sponsored by Abbott Medical Devices.
- Terminated
- Registry status
- Phase 3
- Development phase
- 168
- Enrollment target
NCT00267371: Clinical Trial Phase 3 study, sponsored by Abbott Medical Devices.
NCT00267371 is a Phase 3 study that was terminated before completion, run by Abbott Medical Devices. The registered enrollment target is 168 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00267371, a Phase 3 study, was terminated before completion, sponsored by Abbott Medical Devices.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 168 participants
- Enrollment target
Study Summary
The purpose of this two arm controlled double-blind study is to determine the safety and effectiveness of PFO closure (closing a hole in the wall of the heart) in reducing the frequency of migraine headaches, in patients who experience migraine headaches and have a PFO, compared to medical therapy alone.
Interventions
- DEVICE PFO Closure with Premere investigational device.
- DRUG Medical management/current medications per standard of care by personal physician.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 168 participants |
| Start Date | 2005-11 |
| Est. Completion | 2012-03 |
| Phase | Phase 3 |
Why NCT00267371 stopped before completion
NCT00267371 is an interventional study that assigns participants to a tested intervention. The registered 168 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 2 interventions - of which PFO Closure with Premere investigational device. is the first listed.
NCT00267371 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00267371 about?
NCT00267371 is a clinical study titled "ESCAPE Migraine Trial". The purpose of this two arm controlled double-blind study is to determine the safety and effectiveness of PFO closure (closing a hole in the wall of the heart) in reducing the frequency of migraine headaches, in patients who experience migraine headaches and have a PFO, compared to medical therapy a...
What is the current status of trial NCT00267371?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 168 participants. The study started on 2005-11. Estimated completion is 2012-03.
What interventions are being tested in trial NCT00267371?
The interventions under investigation include: PFO Closure with Premere investigational device. (DEVICE), Medical management/current medications per standard of care by personal physician. (DRUG).
Who is sponsoring clinical trial NCT00267371?
This trial is sponsored by Abbott Medical Devices, which has 261 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00267371's enrollment target sits among peer trials
168 1459th of 2000 higher than 538 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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