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NCT00262730 · ClinicalTrials.gov registry record · Phase 2

Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM

A Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 2
Development phase
97
Enrollment target

NCT00262730 is a Phase 2 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 97 participants.

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The verdict

NCT00262730, a Phase 2 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 2
Development phase
97 participants
Enrollment target

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Biological therapies, such as poly ICLC, may stimulate the immune system in different ways and stop tumor cells from growing. Giving poly ICLC after radiation therapy and temozolomide may stop any remaining tumor cells from growing. PURPOSE: This phase II trial is studying how well giving radiation therapy together with temozolomide followed by temozolomide and poly ICLC works in treating patients with newly diagnosed glioblastoma multiforme.

Interventions

  • DRUG temozolomide
  • RADIATION radiation therapy
  • DRUG poly ICLC

Trial Details

FieldValue
Enrollment Target 97 participants
Start Date 2006-01
Est. Completion 2010-04
Phase Phase 2

What the Registry Record Tells You About NCT00262730

The ClinicalTrials.gov registry entry for NCT00262730 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 97 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which temozolomide is the first listed.

NCT00262730 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00262730 about?

NCT00262730 is a clinical study titled "Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM". RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Biological therapies, such as poly ICLC, may stimulate ...

What is the current status of trial NCT00262730?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 97 participants. The study started on 2006-01. Estimated completion is 2010-04.

What interventions are being tested in trial NCT00262730?

The interventions under investigation include: temozolomide (DRUG), radiation therapy (RADIATION), poly ICLC (DRUG).

Who is sponsoring clinical trial NCT00262730?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.