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NCT00259714 · ClinicalTrials.gov registry record · Phase 1
Dialysate Sodium Individualization in Hemodialysis
A Phase 1 study, sponsored by Yale University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 1
- Enrollment target
NCT00259714: Clinical Trial Phase 1 study, sponsored by Yale University.
NCT00259714 is a Phase 1 study that was terminated before completion, run by Yale University. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00259714, a Phase 1 study, was terminated before completion, sponsored by Yale University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
Salt and water excess is an essential mechanism of hypertension. This is particularly relevant to patients with end stage kidney disease (ESKD) on dialysis. We have demonstrated that individualization of the sodium concentration in the dialysate as to match the patient's own serum sodium concentration leads to less thirst, interdialytic weight gain, and better BP control in hypertensive patients. In this study we will evaluate the mechanisms underlying this response by measuring systemic hemodynamics, body volume spaces, and biochemical marker of volume status.
Interventions
- DRUG dialysate sodium individualization
- DRUG standard dialysate sodium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2006-03 |
| Est. Completion | 2008-04 |
| Phase | Phase 1 |
Why NCT00259714 stopped before completion
NCT00259714 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which dialysate sodium individualization is the first listed.
NCT00259714 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00259714 about?
NCT00259714 is a clinical study titled "Dialysate Sodium Individualization in Hemodialysis". Salt and water excess is an essential mechanism of hypertension. This is particularly relevant to patients with end stage kidney disease (ESKD) on dialysis. We have demonstrated that individualization of the sodium concentration in the dialysate as to match the patient's own serum sodium concentrati...
What is the current status of trial NCT00259714?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2006-03. Estimated completion is 2008-04.
What interventions are being tested in trial NCT00259714?
The interventions under investigation include: dialysate sodium individualization (DRUG), standard dialysate sodium (DRUG).
Who is sponsoring clinical trial NCT00259714?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00259714's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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