Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Pd-103 Dose De-Escalation for Early Stage Prostate Cancer: A Prospective Randomized Trial

NCT00247312 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to determine the most appropriate radiation implant dose for palladium-103 monotherapy. Radiation dose is related to potential cure. From previously published studies, it appears that the prescribed radiation dose can be reduced by 14-20% without any difference in potential cure (in this study, the dose is being decreased 10%). Although most patients tolerate brachytherapy well, complications to appear to be related to radiation exposure to normal structures (i.e. urethra, rectum and proximal penis). By reducing the prescribed dose, it is conceivable that fewer patients will experience side effects and complications.

Conditions Studied

Interventions

  • RADIATION Pd-103

Study Locations (2)

Washington

  • Radiation Oncology 174 Department of Veterans Affairs — Seattle

West Virginia

  • Schiffler Cancer Center — Wheeling

Trial Details

FieldValue
Enrollment Target 319 participants
Start Date 2005-10
Est. Completion 2015-11
Phase Phase 3

Sponsor

Schiffler Cancer Center

2 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00247312

The ClinicalTrials.gov registry entry for NCT00247312 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 319 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Schiffler Cancer Center, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Prostatic Neoplasm appearing as the primary indexed condition, and to 1 intervention — of which Pd-103 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00247312 reports 2 study locations spanning 2 distinct geographic areas — top geographies include Washington, West Virginia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00247312 about?

NCT00247312 is a clinical study titled "Pd-103 Dose De-Escalation for Early Stage Prostate Cancer: A Prospective Randomized Trial". The purpose of this study is to determine the most appropriate radiation implant dose for palladium-103 monotherapy. Radiation dose is related to potential cure. From previously published studies, it appears that the prescribed radiation dose can be reduced by 14-20% without any difference in potent...

What is the current status of trial NCT00247312?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 319 participants. The study started on 2005-10. Estimated completion is 2015-11.

What conditions does trial NCT00247312 study?

This clinical trial studies the following conditions: Prostatic Neoplasm. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00247312?

The interventions under investigation include: Pd-103 (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00247312?

This trial is sponsored by Schiffler Cancer Center, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00247312 being conducted?

This trial has 2 study locations across Washington, West Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial