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NCT00243191 · ClinicalTrials.gov registry record · Phase 2
Neoadjuvant Imatinib in Dermatofibrosarcoma Protuberans
A Phase 2 study, sponsored by Sarcoma Alliance for Research through Collaboration.
- Completed
- Registry status
- Phase 2
- Development phase
- 18
- Enrollment target
NCT00243191: Completed Phase 2 study, sponsored by Sarcoma Alliance for Research through Collaboration.
NCT00243191 is a Phase 2 study that has completed, run by Sarcoma Alliance for Research through Collaboration. The registered enrollment target is 18 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00243191, a Phase 2 study, has completed, sponsored by Sarcoma Alliance for Research through Collaboration.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 18 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the effect of imatinib on dermatofibrosarcoma protuberan tumors.
Primary Outcome
To obtain matched tumor tissue samples of trial participants dermatofibrosarcoma protuberans (DFSP)for the purpose of determining whether imatinib mesylate affects autocrine/paracrine stimulated signal transduction through the platelet-derived growth factor receptor pathway in DFSP by comparing the level of phosphorylated platelet-derived growth factor receptor beta (PDGFRB) in DFSP after up to 2 weeks of treatment with imatinib to the level of phosphorylated PDGFRB pre-treatment.
Interventions
- DRUG imatinib mesylate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2006-05 |
| Est. Completion | 2009-09 |
| Phase | Phase 2 |
What the finished NCT00243191 record still lists
NCT00243191 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 1 intervention - of which imatinib mesylate is the first listed.
NCT00243191 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00243191 about?
NCT00243191 is a clinical study titled "Neoadjuvant Imatinib in Dermatofibrosarcoma Protuberans". The purpose of this study is to examine the effect of imatinib on dermatofibrosarcoma protuberan tumors.
What is the current status of trial NCT00243191?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2006-05. Estimated completion is 2009-09.
What interventions are being tested in trial NCT00243191?
The interventions under investigation include: imatinib mesylate (DRUG).
Who is sponsoring clinical trial NCT00243191?
This trial is sponsored by Sarcoma Alliance for Research through Collaboration, which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00243191's enrollment target sits among peer trials
18 1898th of 2000 higher than 98 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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