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NCT00232479 · ClinicalTrials.gov registry record · Phase 2

Dose Dense Carboplatin, Taxotere and Herceptin As Primary Systemic Therapy in Breast Cancer

A Phase 2 study of Breast Cancer, sponsored by University of Miami.

Completed
Registry status
Phase 2
Development phase
48
Enrollment target
1
Study location

NCT00232479 is a Phase 2 study of Breast Cancer that has completed, run by University of Miami. The registered enrollment target is 48 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00232479, a Phase 2 study of Breast Cancer, has completed, sponsored by University of Miami.

COMPLETED
Registry status
Phase 2
Development phase
48 participants
Enrollment target
1
Study location

Study Summary

Dose dense therapy has been shown to increase survival in the adjuvant setting of breast cancer. It is unknown if dose dense therapy will improve survival in tumors that express her-2. This study evaluates a neoadjuvant regimen containing carboplatin, taxotere and herceptin when used in a dose dense manner in patients with large breast cancers. The endpoint of pathologic complete response is used as a surrogate marker for survival.

Conditions Studied

Interventions

  • DRUG trastuzumab, docetaxel and carboplatin in dose dense regimen

Study Locations (1)

Florida

  • Jackson Memorial Hospital - Miami

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2005-09
Est. Completion 2008-06
Phase Phase 2

Sponsor

University of Miami

721 total trials

What the Registry Record Tells You About NCT00232479

The ClinicalTrials.gov registry entry for NCT00232479 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which trastuzumab, docetaxel and carboplatin in dose dense regimen is the first listed.

NCT00232479 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT00232479 about?

NCT00232479 is a clinical study titled "Dose Dense Carboplatin, Taxotere and Herceptin As Primary Systemic Therapy in Breast Cancer". Dose dense therapy has been shown to increase survival in the adjuvant setting of breast cancer. It is unknown if dose dense therapy will improve survival in tumors that express her-2. This study evaluates a neoadjuvant regimen containing carboplatin, taxotere and herceptin when used in a dose dense...

What is the current status of trial NCT00232479?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 48 participants. The study started on 2005-09. Estimated completion is 2008-06.

What conditions does trial NCT00232479 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT00232479?

The interventions under investigation include: trastuzumab, docetaxel and carboplatin in dose dense regimen (DRUG).

Who is sponsoring clinical trial NCT00232479?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00232479 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.