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NCT00230802 · ClinicalTrials.gov registry record · NA
Thyroid Hormone Dose Adjustment in Pregnancy
A NA study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 48
- Enrollment target
NCT00230802 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 48 participants.
The verdict
NCT00230802, a NA study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
Study Summary
Our aim is to compare the safety and efficacy of 2 different empiric levothyroxine dose adjustment recommendations to be made at the first confirmation of pregnancy in women with a history of hypothyroidism. Subjects will be women with a prior diagnosis of hypothyroidism who are taking thyroid hormone replacement and who are less than 8 weeks pregnant. Upon confirmation of pregnancy, subjects will be randomized to increase their weekly thyroid hormone dose by either 2 or 3 tablets (28 or 42%). Thyroid function will be evaluated every two weeks in the first 20 weeks and then again at week 30 and post-partum. Primary endpoints will be the proportion of women in each group who remain euthyroid throughout the first trimester and throughout pregnancy.
Interventions
- DRUG levothyroxine
- DRUG Anticipatory dose increase of levothyroxine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2005-07 |
| Est. Completion | 2010-07 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00230802
The ClinicalTrials.gov registry entry for NCT00230802 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which levothyroxine is the first listed.
NCT00230802 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00230802 about?
NCT00230802 is a clinical study titled "Thyroid Hormone Dose Adjustment in Pregnancy". Our aim is to compare the safety and efficacy of 2 different empiric levothyroxine dose adjustment recommendations to be made at the first confirmation of pregnancy in women with a history of hypothyroidism. Subjects will be women with a prior diagnosis of hypothyroidism who are taking thyroid hormo...
What is the current status of trial NCT00230802?
This trial is currently completed. It is a NA study. The enrollment target is 48 participants. The study started on 2005-07. Estimated completion is 2010-07.
What interventions are being tested in trial NCT00230802?
The interventions under investigation include: levothyroxine (DRUG), Anticipatory dose increase of levothyroxine (DRUG).
Who is sponsoring clinical trial NCT00230802?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
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