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NCT00229450 · ClinicalTrials.gov registry record · Phase 4
Estrogen and Perimenopausal Depression
A Phase 4 study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- Phase 4
- Development phase
- 17
- Enrollment target
NCT00229450: Completed Phase 4 study, sponsored by University of California, Los Angeles.
NCT00229450 is a Phase 4 study that has completed, run by University of California, Los Angeles. The registered enrollment target is 17 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00229450, a Phase 4 study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 17 participants
- Enrollment target
Study Summary
During perimenopause (the time just prior to menopause), women often notice many biological, psychological, and social changes. In particular, some women experience depressive symptoms during perimenopause that are severe enough to warrant antidepressant medication. Whether or not women with perimenopausal depression respond to antidepressant medication may depend on the level of estrogen in their blood. This study will investigate whether estrogen will help women who only partially respond to antidepressant medications, as well as examine how different doses of estrogen may affect individuals differently.
Primary Outcome
17-item Hamilton Depression (HAM-D17) scores range from 0 to 50, and lower scores are better outcomes.
Interventions
- DRUG Estrogen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2002-04 |
| Est. Completion | 2004-08 |
| Phase | Phase 4 |
What the finished NCT00229450 record still lists
NCT00229450 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Estrogen is the first listed.
NCT00229450 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00229450 about?
NCT00229450 is a clinical study titled "Estrogen and Perimenopausal Depression". During perimenopause (the time just prior to menopause), women often notice many biological, psychological, and social changes. In particular, some women experience depressive symptoms during perimenopause that are severe enough to warrant antidepressant medication. Whether or not women with perimen...
What is the current status of trial NCT00229450?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 17 participants. The study started on 2002-04. Estimated completion is 2004-08.
What interventions are being tested in trial NCT00229450?
The interventions under investigation include: Estrogen (DRUG).
Who is sponsoring clinical trial NCT00229450?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00229450's enrollment target sits among peer trials
17 1854th of 2000 higher than 132 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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