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NCT00221897 · ClinicalTrials.gov registry record
Diagnostic Innovations in Glaucoma Study
A clinical trial of Myopia and Primary Open Angle Glaucoma, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- 3,000
- Enrollment target
- 1
- Study location
NCT00221897 is a study of Myopia and Primary Open Angle Glaucoma that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 3,000 participants, above the 235-participant average among 90 other Myopia trials with a reported enrollment target (1177% higher). The trial reports 1 study location across 1 state.
The verdict
NCT00221897, a study of Myopia and Primary Open Angle Glaucoma, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- 3,000 participants
- Enrollment target
- 1
- Study location
Study Summary
The overarching goal of our research study is to evaluate changes in visual function and optic nerve topography (the structure of the back of the eye) in patients with glaucoma (increased susceptibility to pressure inside the eye that can cause loss of vision) or those with an increased risk of developing the disease. The purpose of this study is to determine the best methods for detecting the presence or progression (worsening over time) of glaucoma in patients with and without myopia and its effects on daily and visual function and quality of life. With several sources of NIH and foundation funding over the last twenty years we have designed a robust research protocol to address the most challenging aspects of glaucoma management. The most recent focus of this research is 1) to improve our ability to detect open angle glaucoma in individuals with myopia and in individuals of European and African descent, 2) to determine whether monitoring of the retinal vasculature with new optical imaging instruments can improve glaucoma management and elucidate the pathophysiology of the disease, and 3) to differentiate between age-related changes and glaucomatous progression. The grants supporting this project include 3 NIH funded studies, 1) the University of California, San Diego UCSD -based "Diagnostic Innovations in Glaucoma Study" (DIGS funded since 1995): 2) the "African Descent and Glaucoma Evaluation Study" (ADAGES funded since 2002), 3) the Brightfocus Foundation National Glaucoma Research Program and 4) the UCSD-based "Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography Angiography" (funded since 2018). The ADAGES is a multi-center study with data collection also conducted at 2 other academic sites, the University of Alabama at Birmingham, and Columbia University. Enrolled healthy participants, glaucoma suspects and glaucoma patients are generally asked to return for two or more visits a year for several years. We then analyze whether the glaucoma
Conditions Studied
Study Locations (1)
California
- UCSD, Hamilton Glaucoma Center - La Jolla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,000 participants |
| Start Date | 1995-04 |
| Est. Completion | 2030-07 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00221897
The ClinicalTrials.gov registry entry for NCT00221897 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 3,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 235-participant average among 90 other Myopia trials with a reported enrollment target (1177% higher). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Myopia appearing as the primary indexed condition, and to 0 interventions.
NCT00221897 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT00221897 about?
NCT00221897 is a clinical study titled "Diagnostic Innovations in Glaucoma Study". The overarching goal of our research study is to evaluate changes in visual function and optic nerve topography (the structure of the back of the eye) in patients with glaucoma (increased susceptibility to pressure inside the eye that can cause loss of vision) or those with an increased risk of deve...
What is the current status of trial NCT00221897?
This trial is currently recruiting. The enrollment target is 3,000 participants. The study started on 1995-04. Estimated completion is 2030-07.
What conditions does trial NCT00221897 study?
This clinical trial studies the following conditions: Myopia, Primary Open Angle Glaucoma.
Who is sponsoring clinical trial NCT00221897?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00221897 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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