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NCT00218439 · ClinicalTrials.gov registry record · NA
Effect of Paroxetine on Smokers' Cardiovascular Response to Stress - 1
A NA study, sponsored by University of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 105
- Enrollment target
NCT00218439: Completed NA study, sponsored by University of Minnesota.
NCT00218439 is a NA study that has completed, run by University of Minnesota. The registered enrollment target is 105 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00218439, a NA study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 105 participants
- Enrollment target
Study Summary
Smokers report that they often smoke cigarettes during stressful times. The combined effect of smoking and exposure to stress leads to exaggerated increases in blood pressure, heart rate and other measures of stress response. This combination may result in greater cardiovascular harm than either smoking or stress alone. The purpose of this study is to determine the effects of paroxetine on the response to stress after smoking.
Primary Outcome
Change in systolic blood pressure from Resting period to that observed during a speech delivered immediately after smoking a cigarette
Interventions
- DRUG Placebo
- DRUG Paroxetine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2005-10 |
| Est. Completion | 2010-08 |
| Phase | NA |
What the finished NCT00218439 record still lists
NCT00218439 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00218439 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00218439 about?
NCT00218439 is a clinical study titled "Effect of Paroxetine on Smokers' Cardiovascular Response to Stress - 1". Smokers report that they often smoke cigarettes during stressful times. The combined effect of smoking and exposure to stress leads to exaggerated increases in blood pressure, heart rate and other measures of stress response. This combination may result in greater cardiovascular harm than either smo...
What is the current status of trial NCT00218439?
This trial is currently completed. It is a NA study. The enrollment target is 105 participants. The study started on 2005-10. Estimated completion is 2010-08.
What interventions are being tested in trial NCT00218439?
The interventions under investigation include: Placebo (DRUG), Paroxetine (DRUG).
Who is sponsoring clinical trial NCT00218439?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00218439's enrollment target sits among peer trials
105 834th of 2000 higher than 1,165 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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