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NCT00205738 · ClinicalTrials.gov registry record · NA
Janssen - Glucose Regulation/Risp/Olanz
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 120
- Enrollment target
NCT00205738 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 120 participants.
The verdict
NCT00205738, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
Study Summary
Abnormalities in peripheral glucose regulation and type 2 diabetes can occur more commonly in individuals with schizophrenia than in healthy subjects or in other psychiatric conditions. Antipsychotic treatment may contribute significantly to abnormalities in glucose regulation. Hyperglycemia can contribute to long-term cardiovascular disease risk that may already be increased in patients with schizophrenia due to higher rates of smoking, sedentary life style, obesity and under-treated hypertension and dyslipidemia. This project will characterize the effects on glucose control of the two most commonly prescribed newer antipsychotic medications, risperidone and olanzapine, in patients with schizophrenia. This proposal specifically hypothesizes that olanzapine treatment will be associated with decreases in insulin sensitivity (SI), without effects on insulin secretion. Treatment-related effects on glucose effectiveness (SG) will be explored.
Interventions
- DRUG Risperidone, Olanzapine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2000-07 |
| Est. Completion | 2006-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00205738
The ClinicalTrials.gov registry entry for NCT00205738 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Risperidone, Olanzapine is the first listed.
NCT00205738 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00205738 about?
NCT00205738 is a clinical study titled "Janssen - Glucose Regulation/Risp/Olanz". Abnormalities in peripheral glucose regulation and type 2 diabetes can occur more commonly in individuals with schizophrenia than in healthy subjects or in other psychiatric conditions. Antipsychotic treatment may contribute significantly to abnormalities in glucose regulation. Hyperglycemia can con...
What is the current status of trial NCT00205738?
This trial is currently completed. It is a NA study. The enrollment target is 120 participants. The study started on 2000-07. Estimated completion is 2006-10.
What interventions are being tested in trial NCT00205738?
The interventions under investigation include: Risperidone, Olanzapine (DRUG).
Who is sponsoring clinical trial NCT00205738?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
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