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NCT00194441 · ClinicalTrials.gov registry record · NA

Cerebral Perfusion Pressure (CPP) Management Information Feedback and Nursing

A NA study of Traumatic Brain Injury and Subarachnoid Hemorrhage, sponsored by University of Washington.

Completed
Registry status
NA
Development phase
260
Enrollment target
1
Study location

NCT00194441 is a NA study of Traumatic Brain Injury and Subarachnoid Hemorrhage that has completed, run by University of Washington. The registered enrollment target is 260 participants, roughly in line with the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target. The trial reports 1 study location across 1 state.

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The verdict

NCT00194441, a NA study of Traumatic Brain Injury and Subarachnoid Hemorrhage, has completed, sponsored by University of Washington.

COMPLETED
Registry status
NA
Development phase
260 participants
Enrollment target
1
Study location

Study Summary

The aim of the initial proposal was to evaluate, in the context of optimal medical management, the impact of a bedside system of cerebral perfusion pressure (CPP) information feedback on nursing moment-to-moment management of CPP, and the relationship of that management to patient functional outcome at discharge, 3 and 6 months. The primary hypothesis being tested is that Glasgow Outcome Score (GOS) 6 months post acute care discharge will be significantly better in those monitored with the continuous CPP display. In the second phase of the study the adult study will be extended to children to determine if there is a critical threshold for CPP in children following brain injury based on their outcome at 3, 6, and 12 months. The primary outcome measure is the GOS at 12 months post-injury. The GOS, Behavior Rating Inventory of Executive Function, and PedsQOL will also be assessed at 3, 6, \& 12 months, and the Adaptive Behavior Assessment System at 3 and 6 months post-injury. In addition, the researchers will examine variability and complexity of physiologic measures, such as blood pressure, recorded during the intensive care unit stay of adults and children enrolled in the study. The researchers will study the association of these measures with risk for secondary brain injury and ability to predict differences in outcome. The researchers will also assess the value individuals place on varying outcomes following brain injury.

Interventions

  • OTHER Bedside display of cerebral perfusion pressure information

Study Locations (1)

Washington

  • University of Washington - Seattle

Trial Details

FieldValue
Enrollment Target 260 participants
Start Date 1999-04
Est. Completion 2008-09
Phase NA

Sponsor

University of Washington

1,048 total trials

What the Registry Record Tells You About NCT00194441

The ClinicalTrials.gov registry entry for NCT00194441 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 260 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target. The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Traumatic Brain Injury appearing as the primary indexed condition, and to 1 intervention - of which Bedside display of cerebral perfusion pressure information is the first listed.

NCT00194441 reports 1 study location spanning 1 distinct geographic area - top geographies include Washington.

Frequently Asked Questions

What is clinical trial NCT00194441 about?

NCT00194441 is a clinical study titled "Cerebral Perfusion Pressure (CPP) Management Information Feedback and Nursing". The aim of the initial proposal was to evaluate, in the context of optimal medical management, the impact of a bedside system of cerebral perfusion pressure (CPP) information feedback on nursing moment-to-moment management of CPP, and the relationship of that management to patient functional outcome...

What is the current status of trial NCT00194441?

This trial is currently completed. It is a NA study. The enrollment target is 260 participants. The study started on 1999-04. Estimated completion is 2008-09.

What conditions does trial NCT00194441 study?

This clinical trial studies the following conditions: Traumatic Brain Injury, Subarachnoid Hemorrhage.

What interventions are being tested in trial NCT00194441?

The interventions under investigation include: Bedside display of cerebral perfusion pressure information (OTHER).

Who is sponsoring clinical trial NCT00194441?

This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00194441 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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