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NCT00193583 · ClinicalTrials.gov registry record · Phase 1
Weekly Topotecan in Combination With Carboplatin in Two Different Schedules for Refractory and/or Advanced Solid Tumors
A Phase 1 study, sponsored by SCRI Development Innovations.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT00193583: Completed Phase 1 study, sponsored by SCRI Development Innovations.
NCT00193583 is a Phase 1 study that has completed, run by SCRI Development Innovations. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00193583, a Phase 1 study, has completed, sponsored by SCRI Development Innovations.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
In this phase I study we will characterize the safety, tolerability, maximum tolerated dose and dose-limiting toxicity of weekly bolus topotecan when administered in combination with two different dosing schedules of carboplatin. We will also evaluate any antitumor activity of these combination regimens.
Interventions
- DRUG Carboplatin
- DRUG Topotecan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2003-05 |
| Est. Completion | 2005-05 |
| Phase | Phase 1 |
What the finished NCT00193583 record still lists
NCT00193583 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Carboplatin is the first listed.
NCT00193583 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00193583 about?
NCT00193583 is a clinical study titled "Weekly Topotecan in Combination With Carboplatin in Two Different Schedules for Refractory and/or Advanced Solid Tumors". In this phase I study we will characterize the safety, tolerability, maximum tolerated dose and dose-limiting toxicity of weekly bolus topotecan when administered in combination with two different dosing schedules of carboplatin. We will also evaluate any antitumor activity of these combination regi...
What is the current status of trial NCT00193583?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2003-05. Estimated completion is 2005-05.
What interventions are being tested in trial NCT00193583?
The interventions under investigation include: Carboplatin (DRUG), Topotecan (DRUG).
Who is sponsoring clinical trial NCT00193583?
This trial is sponsored by SCRI Development Innovations, which has 146 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00193583's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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