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COMPLETED Phase 2

A Study of Rituximab and Bevacizumab in Patients With Follicular Non-Hodgkin's Lymphoma

NCT00193492 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the feasibility, efficacy and safety of adding bevacizumab to rituximab compared to rituximab alone in patients with previously treated follicular non-hodgkin's lymphoma (NHL) whose disease has progressed following at least one previous chemotherapy regimen and not more than 2 previous chemotherapy regimens.

Conditions Studied

Interventions

  • DRUG Bevacizumab
  • DRUG Rituximab

Study Locations (20)

Florida

  • Florida Cancer Specialists — Fort Myers
  • Integrated Community Oncology Network — Jacksonville
  • Watson Clinic for Cancer Research — Lakeland
  • Florida Hospital Cancer Institute — Orlando

Georgia

  • Medical Oncology Associates of Augusta — Augusta
  • Northeast Georgia Medical Center — Gainesville
  • Wellstar Cancer Research — Marietta

Kentucky

  • Graves-Gilbert Clinic — Bowling Green
  • Baptist Hospital East — Louisville
  • Norton Cancer Institute — Louisville

Maryland

  • Center for Cancer and Blood Disorders — Bethesda
  • National Capital Clinical Research Consortium — Bethesda

Arkansas

  • Northeast Arkansas Clinic — Jonesboro

Indiana

  • Providence Medical Group — Terre Haute

Louisiana

  • Hematology Oncology Clinic, LLP — Baton Rouge

Nebraska

  • Methodist Cancer Center — Omaha

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2005-09
Est. Completion 2013-03
Phase Phase 2

Sponsor

SCRI Development Innovations

63 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00193492

The ClinicalTrials.gov registry entry for NCT00193492 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SCRI Development Innovations, which has 63 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Lymphoma, Follicular appearing as the primary indexed condition, and to 2 interventions — of which Bevacizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00193492 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, Georgia, Kentucky. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00193492 about?

NCT00193492 is a clinical study titled "A Study of Rituximab and Bevacizumab in Patients With Follicular Non-Hodgkin's Lymphoma". The purpose of this study is to assess the feasibility, efficacy and safety of adding bevacizumab to rituximab compared to rituximab alone in patients with previously treated follicular non-hodgkin's lymphoma (NHL) whose disease has progressed following at least one previous chemotherapy regimen and...

What is the current status of trial NCT00193492?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2005-09. Estimated completion is 2013-03.

What conditions does trial NCT00193492 study?

This clinical trial studies the following conditions: Lymphoma, Follicular. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00193492?

The interventions under investigation include: Bevacizumab (DRUG), Rituximab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00193492?

This trial is sponsored by SCRI Development Innovations, which has 63 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00193492 being conducted?

This trial has 20 study locations across Arkansas, Florida, Georgia, Indiana, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial