Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00177177 · ClinicalTrials.gov registry record · NA

L-carnosine for Schizophrenia

A NA study, sponsored by University of Pittsburgh.

Completed
Registry status
NA
Development phase
84
Enrollment target

NCT00177177: Completed NA study, sponsored by University of Pittsburgh.

NCT00177177 is a NA study that has completed, run by University of Pittsburgh. The registered enrollment target is 84 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00177177, a NA study, has completed, sponsored by University of Pittsburgh.

COMPLETED
Registry status
NA
Development phase
84 participants
Enrollment target

Study Summary

The investigators' hypothesis is that oral L-carnosine treatment (as compared with placebo) will enhance cognitive abilities (specifically: measures of attention, executive function, working memory, visuospatial ability and language) in persons with schizophrenia or schizoaffective disorder. Secondarily, they hypothesize that there will be secondary improvements in positive, negative and mood symptoms with L-carnosine treatment. The investigators aim to test these hypotheses by conducting a randomized, placebo controlled, add-on treatment trial of L-carnosine (added to existing antipsychotic treatment) up to 84 recruited subjects with Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR) schizophrenia/schizoaffective disorder for a period of 16 weeks. Measures of cognition and psychopathology will be utilized for evaluating primary and secondary outcomes, along with safety assessments.

Interventions

  • DRUG L-carnosine (dietary supplement)

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2004-03
Est. Completion 2007-12
Phase NA
University of Pittsburgh

1,238 total trials

What the finished NCT00177177 record still lists

NCT00177177 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which L-carnosine (dietary supplement) is the first listed.

NCT00177177 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00177177 about?

NCT00177177 is a clinical study titled "L-carnosine for Schizophrenia". The investigators' hypothesis is that oral L-carnosine treatment (as compared with placebo) will enhance cognitive abilities (specifically: measures of attention, executive function, working memory, visuospatial ability and language) in persons with schizophrenia or schizoaffective disorder. Seconda...

What is the current status of trial NCT00177177?

This trial is currently completed. It is a NA study. The enrollment target is 84 participants. The study started on 2004-03. Estimated completion is 2007-12.

What interventions are being tested in trial NCT00177177?

The interventions under investigation include: L-carnosine (dietary supplement) (DRUG).

Who is sponsoring clinical trial NCT00177177?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00177177's enrollment target sits among peer trials

84 983rd of 2000 higher than 1,011 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02391519 · 84 participants

    Effects of High Altitude on AMPK Activation

  • NCT03838536 · 84 participants · NA

    Synergistic Activity of Human Milk Nutrients and Infant Cognition

  • NCT03884075 · 84 participants · Phase 2

    Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

  • NCT03894917 · 84 participants

    Characterizing Disease Biology, Treatment and Toxicity in Older Adults With Hepatocellular Carcinoma

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00177177, the US trial registry maintained by the National Library of Medicine. NCT00177177 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.