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NCT00176917 · ClinicalTrials.gov registry record · Phase 2

Stem Cell Transplantation for Hurler

A Phase 2 study of Mucopolysaccharidosis VI and Mucopolysaccharidosis I, sponsored by Masonic Cancer Center, University of Minnesota.

Completed
Registry status
Phase 2
Development phase
41
Enrollment target
1
Study location

NCT00176917 is a Phase 2 study of Mucopolysaccharidosis VI and Mucopolysaccharidosis I that has completed, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 41 participants, below the 62-participant average among 6 other Mucopolysaccharidosis VI trials with a reported enrollment target (34% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00176917, a Phase 2 study of Mucopolysaccharidosis VI and Mucopolysaccharidosis I, has completed, sponsored by Masonic Cancer Center, University of Minnesota.

COMPLETED
Registry status
Phase 2
Development phase
41 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine the safety and engraftment of donor hematopoietic cells using this conditioning regimen in patients undergoing a hematopoietic (blood forming) cell transplant for Hurler syndrome, Maroteaux Lamy syndrome, Mannosidosis, or I-cell disease.

Interventions

  • PROCEDURE Stem Cell Transplant
  • DRUG Busulfan, Cyclophosphamide, ATG

Study Locations (1)

Minnesota

  • Masonic Cancer Center, University of Minnesota - Minneapolis

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 1999-05
Est. Completion 2010-05
Phase Phase 2

What the Registry Record Tells You About NCT00176917

The ClinicalTrials.gov registry entry for NCT00176917 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 62-participant average among 6 other Mucopolysaccharidosis VI trials with a reported enrollment target (34% lower). The listed sponsor is Masonic Cancer Center, University of Minnesota, which has 249 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Mucopolysaccharidosis VI appearing as the primary indexed condition, and to 2 interventions - of which Stem Cell Transplant is the first listed.

NCT00176917 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT00176917 about?

NCT00176917 is a clinical study titled "Stem Cell Transplantation for Hurler". The purpose of this study is to determine the safety and engraftment of donor hematopoietic cells using this conditioning regimen in patients undergoing a hematopoietic (blood forming) cell transplant for Hurler syndrome, Maroteaux Lamy syndrome, Mannosidosis, or I-cell disease.

What is the current status of trial NCT00176917?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 41 participants. The study started on 1999-05. Estimated completion is 2010-05.

What conditions does trial NCT00176917 study?

This clinical trial studies the following conditions: Mucopolysaccharidosis VI, Mucopolysaccharidosis I, Mannosidosis, Mucolipidosis Type II (I-cell Disease).

What interventions are being tested in trial NCT00176917?

The interventions under investigation include: Stem Cell Transplant (PROCEDURE), Busulfan, Cyclophosphamide, ATG (DRUG).

Who is sponsoring clinical trial NCT00176917?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00176917 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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