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NCT00168337 · ClinicalTrials.gov registry record · Phase 3

A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema

A Phase 3 study, sponsored by Allergan.

Completed
Registry status
Phase 3
Development phase
554
Enrollment target

NCT00168337: Completed Phase 3 study, sponsored by Allergan.

NCT00168337 is a Phase 3 study that has completed, run by Allergan. The registered enrollment target is 554 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (28% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00168337, a Phase 3 study, has completed, sponsored by Allergan.

COMPLETED
Registry status
Phase 3
Development phase
554 participants
Enrollment target

Study Summary

This study will evaluate the safety and efficacy of an intravitreal implant of dexamethasone for the treatment of diabetic macular edema.

Primary Outcome

BCVA is measured using an eye chart and is reported as the number of letters read correctly (ranging from 0 to 100 letters) in the study eye. The lower the number of letters read correctly on the eye chart, the worse the vision (or visual acuity). An increase in the number of letters read correctly indicates improvement and a decrease in the number of letters read correctly indicates a worsening.

Interventions

  • DRUG Dexamethasone
  • OTHER Sham

Trial Details

FieldValue
Enrollment Target 554 participants
Start Date 2005-05
Est. Completion 2012-05
Phase Phase 3
Allergan

314 total trials

What the finished NCT00168337 record still lists

NCT00168337 is an interventional study that assigns participants to a tested intervention. The registered 554 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (28% lower).

The record links to 0 conditions, and to 2 interventions - of which Dexamethasone is the first listed.

NCT00168337 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00168337 about?

NCT00168337 is a clinical study titled "A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema". This study will evaluate the safety and efficacy of an intravitreal implant of dexamethasone for the treatment of diabetic macular edema.

What is the current status of trial NCT00168337?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 554 participants. The study started on 2005-05. Estimated completion is 2012-05.

What interventions are being tested in trial NCT00168337?

The interventions under investigation include: Dexamethasone (DRUG), Sham (OTHER).

Who is sponsoring clinical trial NCT00168337?

This trial is sponsored by Allergan, which has 314 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00168337's enrollment target sits among peer trials

554 678th of 2000 higher than 1,323 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00168337, the US trial registry maintained by the National Library of Medicine. NCT00168337 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.