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NCT00166400 · ClinicalTrials.gov registry record · Phase 4
A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation.
A Phase 4 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 4
- Development phase
- 60
- Enrollment target
NCT00166400: Completed Phase 4 study, sponsored by Mayo Clinic.
NCT00166400 is a Phase 4 study that has completed, run by Mayo Clinic. The registered enrollment target is 60 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00166400, a Phase 4 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 60 participants
- Enrollment target
Study Summary
Mitral valve regurgitation (leakage of the mitral valve of the heart) is frequent and currently there is no specific medical therapy. Mitral regurgitation is a slowly progressive disease that frequently requires surgical treatment. This randomized clinical trial will use Metoprolol, a common beta-blocker medication, to determine if medical treatment impacts mitral valve disease progression.
Interventions
- DRUG metoprolol succinate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2004-07 |
| Est. Completion | 2007-07 |
| Phase | Phase 4 |
What the finished NCT00166400 record still lists
NCT00166400 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 1 intervention - of which metoprolol succinate is the first listed.
NCT00166400 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00166400 about?
NCT00166400 is a clinical study titled "A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation.". Mitral valve regurgitation (leakage of the mitral valve of the heart) is frequent and currently there is no specific medical therapy. Mitral regurgitation is a slowly progressive disease that frequently requires surgical treatment. This randomized clinical trial will use Metoprolol, a common beta-bl...
What is the current status of trial NCT00166400?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2004-07. Estimated completion is 2007-07.
What interventions are being tested in trial NCT00166400?
The interventions under investigation include: metoprolol succinate (DRUG).
Who is sponsoring clinical trial NCT00166400?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00166400's enrollment target sits among peer trials
60 1125th of 2000 higher than 799 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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