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NCT00151164 · ClinicalTrials.gov registry record · Phase 2
Thymic Tolerance in Pediatric Heart Transplantation
A Phase 2 study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Terminated
- Registry status
- Phase 2
- Development phase
- 48
- Enrollment target
NCT00151164: Clinical Trial Phase 2 study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT00151164 is a Phase 2 study that was terminated before completion, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 48 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00151164, a Phase 2 study, was terminated before completion, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 48 participants
- Enrollment target
Study Summary
The investigators hypothesize that injecting donor bone marrow cells into the recipient thymus gland at the time of heart transplantation in children will prove to be feasible and safe. They further hypothesize that recipients receiving donor bone marrow will experience less acute rejection events with reduced long-term requirements for immunosuppressive medications when compared to controls who do not receive marrow but who are managed under an identical immunosuppressive protocol.
Interventions
- PROCEDURE donor bone marrow cell injection into thymus gland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2004-04 |
| Est. Completion | 2007-10 |
| Phase | Phase 2 |
Why NCT00151164 stopped before completion
NCT00151164 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower).
The record links to 0 conditions, and to 1 intervention - of which donor bone marrow cell injection into thymus gland is the first listed.
NCT00151164 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00151164 about?
NCT00151164 is a clinical study titled "Thymic Tolerance in Pediatric Heart Transplantation". The investigators hypothesize that injecting donor bone marrow cells into the recipient thymus gland at the time of heart transplantation in children will prove to be feasible and safe. They further hypothesize that recipients receiving donor bone marrow will experience less acute rejection events w...
What is the current status of trial NCT00151164?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 48 participants. The study started on 2004-04. Estimated completion is 2007-10.
What interventions are being tested in trial NCT00151164?
The interventions under investigation include: donor bone marrow cell injection into thymus gland (PROCEDURE).
Who is sponsoring clinical trial NCT00151164?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00151164's enrollment target sits among peer trials
48 1265th of 2000 higher than 718 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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