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NCT00147485 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Study Of An Intravenously Administered Cyclin-Dependent Kinase Inhibitor In Patients With Advanced Cancer

A Phase 1 study, sponsored by Pfizer.

Terminated
Registry status
Phase 1
Development phase
37
Enrollment target

NCT00147485: Clinical Trial Phase 1 study, sponsored by Pfizer.

NCT00147485 is a Phase 1 study that was terminated before completion, run by Pfizer. The registered enrollment target is 37 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (38% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00147485, a Phase 1 study, was terminated before completion, sponsored by Pfizer.

TERMINATED
Registry status
Phase 1
Development phase
37 participants
Enrollment target

Study Summary

AG-024322 may work in cancer by stopping cancer cells from multiplying. AG-024322 is and intravenous drug from a new class of drugs call cyclin-dependent kinase (CDK inhibitors). This research study is the first time that AG-024322 will be given to people.

Interventions

  • DRUG AG-024322

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2004-12
Est. Completion 2007-08
Phase Phase 1
Pfizer

1,845 total trials

Why NCT00147485 stopped before completion

NCT00147485 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (38% lower).

The record links to 0 conditions, and to 1 intervention - of which AG-024322 is the first listed.

NCT00147485 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00147485 about?

NCT00147485 is a clinical study titled "A Phase 1 Study Of An Intravenously Administered Cyclin-Dependent Kinase Inhibitor In Patients With Advanced Cancer". AG-024322 may work in cancer by stopping cancer cells from multiplying. AG-024322 is and intravenous drug from a new class of drugs call cyclin-dependent kinase (CDK inhibitors). This research study is the first time that AG-024322 will be given to people.

What is the current status of trial NCT00147485?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2004-12. Estimated completion is 2007-08.

What interventions are being tested in trial NCT00147485?

The interventions under investigation include: AG-024322 (DRUG).

Who is sponsoring clinical trial NCT00147485?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00147485's enrollment target sits among peer trials

37 1204th of 2000 higher than 791 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00147485, the US trial registry maintained by the National Library of Medicine. NCT00147485 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.