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NCT00142818 · ClinicalTrials.gov registry record · Phase 2
Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence
A Phase 2 study, sponsored by Kyle Kampman.
- Completed
- Registry status
- Phase 2
- Development phase
- 164
- Enrollment target
NCT00142818: Completed Phase 2 study, sponsored by Kyle Kampman.
NCT00142818 is a Phase 2 study that has completed, run by Kyle Kampman. The registered enrollment target is 164 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00142818, a Phase 2 study, has completed, sponsored by Kyle Kampman.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 164 participants
- Enrollment target
Study Summary
Modafinil is a medication that may enhance mood and increase energy in cocaine addicts, which may be useful in preventing cocaine relapse. Naltrexone is a medication that is currently used to treat drug and alcohol addiction. A combination of these two medications may be beneficial in reducing drug and alcohol use in individuals undergoing substance abuse treatment. The purpose of this study is to evaluate the effectiveness of modafinil and naltrexone, alone and in combination, at reducing drug and alcohol use in individuals addicted to cocaine and alcohol.
Interventions
- DRUG Placebo
- DRUG Modafinil
- DRUG Naltrexone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 164 participants |
| Start Date | 2006-02 |
| Est. Completion | 2013-08 |
| Phase | Phase 2 |
What the finished NCT00142818 record still lists
NCT00142818 is an interventional study that assigns participants to a tested intervention. The registered 164 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% higher).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT00142818 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00142818 about?
NCT00142818 is a clinical study titled "Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence". Modafinil is a medication that may enhance mood and increase energy in cocaine addicts, which may be useful in preventing cocaine relapse. Naltrexone is a medication that is currently used to treat drug and alcohol addiction. A combination of these two medications may be beneficial in reducing drug ...
What is the current status of trial NCT00142818?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 164 participants. The study started on 2006-02. Estimated completion is 2013-08.
What interventions are being tested in trial NCT00142818?
The interventions under investigation include: Placebo (DRUG), Modafinil (DRUG), Naltrexone (DRUG).
Who is sponsoring clinical trial NCT00142818?
This trial is sponsored by Kyle Kampman, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00142818's enrollment target sits among peer trials
164 413th of 2000 higher than 1,583 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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