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NCT00142493 · ClinicalTrials.gov registry record · Phase 1
Effect of Affective Content on Drug Induced Amnesia of Episodic Memory
A Phase 1 study, sponsored by Memorial Sloan Kettering Cancer Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 79
- Enrollment target
NCT00142493: Completed Phase 1 study, sponsored by Memorial Sloan Kettering Cancer Center.
NCT00142493 is a Phase 1 study that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 79 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00142493, a Phase 1 study, has completed, sponsored by Memorial Sloan Kettering Cancer Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 79 participants
- Enrollment target
Study Summary
The purpose of this research is to understand how some of the drugs commonly used in anesthesia impair memory. We are particularly interested in whether the emotion associated with a memory influences how well these drugs are able to block memory. We are studying four commonly used drugs-propofol, thiopental, midazolam, and dexmedetomidine, all of which may have slightly differing effects. We will also study an inactive substance, called a placebo, that should have no effect. The results of this study will provide information that will be useful in understanding how memory works, how these drugs affect memory, and possibly why some people don't have their memory blocked as easily as others.
Interventions
- DRUG placebo
- DRUG Propofol
- DRUG Midazolam Hydrochloride
- DRUG Dexmedetomidine Hydrochloride
- DRUG Thiopental Sodium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 79 participants |
| Start Date | 2004-09 |
| Est. Completion | 2008-08 |
| Phase | Phase 1 |
What the finished NCT00142493 record still lists
NCT00142493 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 79 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% higher).
The record links to 0 conditions, and to 5 interventions - of which placebo is the first listed.
NCT00142493 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00142493 about?
NCT00142493 is a clinical study titled "Effect of Affective Content on Drug Induced Amnesia of Episodic Memory". The purpose of this research is to understand how some of the drugs commonly used in anesthesia impair memory. We are particularly interested in whether the emotion associated with a memory influences how well these drugs are able to block memory. We are studying four commonly used drugs-propofol, t...
What is the current status of trial NCT00142493?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 79 participants. The study started on 2004-09. Estimated completion is 2008-08.
What interventions are being tested in trial NCT00142493?
The interventions under investigation include: placebo (DRUG), Propofol (DRUG), Midazolam Hydrochloride (DRUG), Dexmedetomidine Hydrochloride (DRUG), Thiopental Sodium (DRUG).
Who is sponsoring clinical trial NCT00142493?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00142493's enrollment target sits among peer trials
79 696th of 2000 higher than 1,304 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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