Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00135720 · ClinicalTrials.gov registry record · Phase 2

Study of Etanercept (Enbrel) in the Treatment of Pemphigus Vulgaris

A Phase 2 study, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 2
Development phase
12
Enrollment target

NCT00135720: Completed Phase 2 study, sponsored by Massachusetts General Hospital.

NCT00135720 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT00135720, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 2
Development phase
12 participants
Enrollment target

Study Summary

The purpose of the study is to find out about the effectiveness and the safety of an investigational drug called etanercept (Enbrel) to treat pemphigus vulgaris. Pemphigus vulgaris is a potentially life threatening blistering condition that currently has no cure. An investigational drug is one that has not been approved by the United States (US) Food and Drug Administration (FDA) to treat a particular condition or disease. Etanercept has been approved by the FDA to treat rheumatoid arthritis, juvenile rheumatoid arthritis, and psoriasis, but not pemphigus vulgaris.

Interventions

  • DRUG Enbrel (Etanercept)

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2004-06
Est. Completion 2007-11
Phase Phase 2
Massachusetts General Hospital

2,032 total trials

What the finished NCT00135720 record still lists

NCT00135720 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 1 intervention - of which Enbrel (Etanercept) is the first listed.

NCT00135720 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00135720 about?

NCT00135720 is a clinical study titled "Study of Etanercept (Enbrel) in the Treatment of Pemphigus Vulgaris". The purpose of the study is to find out about the effectiveness and the safety of an investigational drug called etanercept (Enbrel) to treat pemphigus vulgaris. Pemphigus vulgaris is a potentially life threatening blistering condition that currently has no cure. An investigational drug is one that...

What is the current status of trial NCT00135720?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2004-06. Estimated completion is 2007-11.

What interventions are being tested in trial NCT00135720?

The interventions under investigation include: Enbrel (Etanercept) (DRUG).

Who is sponsoring clinical trial NCT00135720?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00135720's enrollment target sits among peer trials

12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02602769 · 12 participants

    Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

  • NCT02605421 · 12 participants · Phase 2

    Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

  • NCT02619448 · 12 participants · Early Phase 1

    Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

  • NCT03311503 · 12 participants · Phase 1

    Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00135720, the US trial registry maintained by the National Library of Medicine. NCT00135720 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.