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NCT00129246 · ClinicalTrials.gov registry record · Phase 1
Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain
A Phase 1 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT00129246: Completed Phase 1 study, sponsored by Yale University.
NCT00129246 is a Phase 1 study that has completed, run by Yale University. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00129246, a Phase 1 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain.
Primary Outcome
Smoking cessation is defined as the number of patients that displayed continuous 6-week abstinence from the quit date.
Interventions
- DRUG Bupropion
- DRUG Naltrexone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2004-12 |
| Est. Completion | 2005-12 |
| Phase | Phase 1 |
What the finished NCT00129246 record still lists
NCT00129246 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 2 interventions - of which Bupropion is the first listed.
NCT00129246 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00129246 about?
NCT00129246 is a clinical study titled "Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain". This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain.
What is the current status of trial NCT00129246?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2004-12. Estimated completion is 2005-12.
What interventions are being tested in trial NCT00129246?
The interventions under investigation include: Bupropion (DRUG), Naltrexone (DRUG).
Who is sponsoring clinical trial NCT00129246?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00129246's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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