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NCT00128635 · ClinicalTrials.gov registry record · Phase 1

Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

A Phase 1 study, sponsored by Abramson Cancer Center at Penn Medicine.

Completed
Registry status
Phase 1
Development phase
22
Enrollment target

NCT00128635 is a Phase 1 study that has completed, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 22 participants.

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The verdict

NCT00128635, a Phase 1 study, has completed, sponsored by Abramson Cancer Center at Penn Medicine.

COMPLETED
Registry status
Phase 1
Development phase
22 participants
Enrollment target

Study Summary

RATIONALE: Radiolabeled monoclonal antibodies, such as iodine I 131 monoclonal antibody TNT-1/B (\^131I MOAB TNT-1/B), can find tumor cells and carry tumor-killing substances to them without harming normal cells. This may be an effective treatment for glioblastoma multiforme. PURPOSE: This phase I trial is studying the side effects and best dose of \^131I MOAB TNT-1/B in treating patients with progressive or recurrent glioblastoma multiforme.

Interventions

  • RADIATION iodine I 131 monoclonal antibody TNT-1/B

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2005-10
Est. Completion 2007-10
Phase Phase 1

What the Registry Record Tells You About NCT00128635

The ClinicalTrials.gov registry entry for NCT00128635 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abramson Cancer Center at Penn Medicine, which has 402 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which iodine I 131 monoclonal antibody TNT-1/B is the first listed.

NCT00128635 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00128635 about?

NCT00128635 is a clinical study titled "Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme". RATIONALE: Radiolabeled monoclonal antibodies, such as iodine I 131 monoclonal antibody TNT-1/B (\^131I MOAB TNT-1/B), can find tumor cells and carry tumor-killing substances to them without harming normal cells. This may be an effective treatment for glioblastoma multiforme. PURPOSE: This phase I ...

What is the current status of trial NCT00128635?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2005-10. Estimated completion is 2007-10.

What interventions are being tested in trial NCT00128635?

The interventions under investigation include: iodine I 131 monoclonal antibody TNT-1/B (RADIATION).

Who is sponsoring clinical trial NCT00128635?

This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.