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NCT00123539 · ClinicalTrials.gov registry record · NA

Estrogen Replacement to Reduce Risk of Neurologic Injury After Coronary Artery Bypass Graft Surgery

A NA study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

Terminated
Registry status
NA
Development phase
334
Enrollment target

NCT00123539: Clinical Trial NA study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

NCT00123539 is a NA study that was terminated before completion, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 334 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (76% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00123539, a NA study, was terminated before completion, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

TERMINATED
Registry status
NA
Development phase
334 participants
Enrollment target

Study Summary

The purpose of this study is to test whether perioperative estrogen replacement in postmenopausal women reduces the risk for neurologic injury after coronary artery bypass graft (CABG) surgery.

Interventions

  • PROCEDURE Surgery
  • DRUG Estrogen Replacement Therapy

Trial Details

FieldValue
Enrollment Target 334 participants
Start Date 2001-06
Est. Completion 2005-08
Phase NA

Why NCT00123539 stopped before completion

NCT00123539 is an interventional study that assigns participants to a tested intervention. The registered 334 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (76% lower).

The record links to 0 conditions, and to 2 interventions - of which Surgery is the first listed.

NCT00123539 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00123539 about?

NCT00123539 is a clinical study titled "Estrogen Replacement to Reduce Risk of Neurologic Injury After Coronary Artery Bypass Graft Surgery". The purpose of this study is to test whether perioperative estrogen replacement in postmenopausal women reduces the risk for neurologic injury after coronary artery bypass graft (CABG) surgery.

What is the current status of trial NCT00123539?

This trial is currently terminated. It is a NA study. The enrollment target is 334 participants. The study started on 2001-06. Estimated completion is 2005-08.

What interventions are being tested in trial NCT00123539?

The interventions under investigation include: Surgery (PROCEDURE), Estrogen Replacement Therapy (DRUG).

Who is sponsoring clinical trial NCT00123539?

This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00123539's enrollment target sits among peer trials

334 305th of 2000 higher than 1,695 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00123539, the US trial registry maintained by the National Library of Medicine. NCT00123539 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.