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NCT00117715 · ClinicalTrials.gov registry record
Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body
A clinical trial, sponsored by Children's Mercy Hospital Kansas City.
- Completed
- Registry status
- 121
- Enrollment target
NCT00117715: Completed study, sponsored by Children's Mercy Hospital Kansas City.
NCT00117715 is a clinical trial that has completed, run by Children's Mercy Hospital Kansas City. The registered enrollment target is 121 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00117715 has completed, sponsored by Children's Mercy Hospital Kansas City.
- COMPLETED
- Registry status
- 121 participants
- Enrollment target
Study Summary
This is a drug metabolism study in one-year old children involving caffeine and dextromethorphan.
Primary Outcome
Concentrations of dextromethorphan(DM) and it's metabolite dextrorphan (DX) are quantified in urine and used to estimate the activity of cytochromes P450 2D6 using the well established DM/DX ratio. The longitudinal study design allows for changes in drug metabolism activity as a function of age which can be characterized via least squares regression where the slope of age vs. DM/DX ratio is examined for deviations from zero.
Interventions
- PROCEDURE Genotyping and Phenotyping using dextromethorphan and caffeine as probes
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 121 participants |
| Start Date | 2000-10 |
| Est. Completion | 2010-01 |
What the finished NCT00117715 record still lists
NCT00117715 is an observational study that tracks outcomes without assigning an intervention. The registered 121 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Genotyping and Phenotyping using dextromethorphan and caffeine as probes is the first listed.
NCT00117715 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00117715 about?
NCT00117715 is a clinical study titled "Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body". This is a drug metabolism study in one-year old children involving caffeine and dextromethorphan.
What is the current status of trial NCT00117715?
This trial is currently completed. The enrollment target is 121 participants. The study started on 2000-10. Estimated completion is 2010-01.
What interventions are being tested in trial NCT00117715?
The interventions under investigation include: Genotyping and Phenotyping using dextromethorphan and caffeine as probes (PROCEDURE).
Who is sponsoring clinical trial NCT00117715?
This trial is sponsored by Children's Mercy Hospital Kansas City, which has 184 total clinical trials registered on ClinicalTrials.gov.
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